Publications by authors named "Si-Rui Yang"

Article Synopsis
  • A study focused on adenosine deaminase 2 deficiency (DADA2) in a Chinese population was conducted to analyze clinical characteristics and responses to treatment, using data from 17 rheumatology centers.
  • Thirty patients were identified, with most showing symptoms like systemic inflammation and vasculitis; the median ages for disease presentation and diagnosis were 4.3 years and 7.8 years, respectively.
  • The research concluded that genetic screening and testing are crucial for early diagnosis, recommending TNF inhibitors as first-line treatment, and hematopoietic stem cell transplantation for specific cases.
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Colloidal quantum dots (QDs) as photocatalysts enable catalysis of CO-to-CO conversion in the presence of electron donors. The surface and/or interfacial chemical environment of the QDs is essential for the activity and selectivity of the CO photoreduction. Various strategies, including exposing active metal sites or anchoring functional organic ligands, have been applied to tune the QDs' surface chemical environment and thus to improve both activity and selectivity of CO photoreduction, which occurs at surface of the QDs.

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Article Synopsis
  • Epigenetics is about how genes can be turned on or off without changing the actual DNA sequence!
  • Microbes can change how our immune system works by using epigenetics, which helps them avoid being attacked!
  • Oral bacteria can influence inflammation in our body, and this article talks about how these bacteria might help us understand oral diseases better!
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Background: Macrophage activation syndrome (MAS) is a major cause of morbidity and mortality in pediatric rheumatology. We aimed to further understand the clinical features, treatment, and outcome of MAS in China.

Methods: A multi-center cohort study was performed in seven hospitals in China from 2012 to 2018.

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Background: Systemic lupus erythematosis (SLE) is a complex and clinically heterogeneous autoimmune disease. A variety of immunological defects contribute to SLE, including dysregulated innate and adaptive immune response. A clearer understanding of the mechanisms driving disease pathogenesis combined with recent advances in medical science is predicted to enable accelerated progress towards improved SLE-personalized approaches to treatment.

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Astragaloside is one of the most common traditional Chinese medicines and is derived from Astragalus membranaceus. Astragaloside IV (AsIV) is a monomer located in an extract of astragaloside. The current study investigated the protective effects of AsIV against hydrogen peroxide (H2O2)-induced injury in cardiocytes and elucidated the mechanisms responsible for this protective effect.

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Background: Ventricular septal defect (VSD) is the most frequent type of congenital heart disease. Conventional methods to evaluate VSD size and severity are both invasive and cumbersome to perform. We investigated whether the ratio between the diameter of the defect and the aortic root diameter (DVSD/DAR) would accurately reflect the degree of shunted blood and the severity of VSD in children with perimembranous VSD.

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Objective: To determine the association between heart rate variability (HRV) and hypertension in Chinese children.

Methods: The study was conducted in First Hospital of Jilin University, China. A total of 101 children were recruited in this study.

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In this study, we report one case of a three-year-old boy infected with Mycoplasma pneumonia (MP) and presenting concomitant multiple organ damage of the heart, kidney, lung and liver, among others, together with a brief review for the diagnosis and treatment of MP infection with multiple organ dysfunction syndrome (MODS).

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