Publications by authors named "Si-Rong Song"
Recent studies have revealed that glioma-associated mesenchymal stem cells play instrumental roles in tumorigenesis and tumour progression and cannot be ignored as a cellular component of the glioma microenvironment. Nevertheless, the origin of these cells and their roles are poorly understood. The only relevant studies have shown that glioma-associated mesenchymal stem cells play a large role in promoting tumour proliferation, invasion and angiogenesis.
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- White matter tracts (WMs) are key pathways for glioblastoma multiforme (GBM) invasion, but research into this process is limited by inadequate models.
- Various in vitro models, such as nerve fiber cultures, brain slice cultures, organoids, and microfluidic chips, have been developed to better replicate the brain's environment and study GBM invasion.
- These advanced models allow for a deeper understanding of GBM's behavior in relation to WMs, perineural invasion, and how other solid tumors metastasize in the brain.