Asymmetric Synthesis of Trisubstituted Vicinal Diols through Copper(I)-Catalyzed Diastereoselective and Enantioselective Allylation of Ketones with Siloxypropadienes.

Chiral trisubstituted vicinal diols are a type of important organic compounds, serving as both common structure units in bioactive natural products and chiral auxiliaries in asymmetric synthesis. Herein, by using siloxypropadienes as the precursors of allyl copper(I) species, a copper(I)-catalyzed diastereoselective and enantioselective reductive allylation of ketones was achieved, providing both syn-diols and anti-diols in good to excellent enantioselectivity. DFT calculations show that cis-γ-siloxy-allyl copper species are generated favorably with either 1-TBSO-propadiene or 1-TIPSO-propadiene.

Study on Bulk Texture and Mechanical Properties of As-Extruded Wide Mg-Al-Zn Alloy Sheets with Different Al Addition.

The wide Mg alloy sheets produced by hot extrusion usually can easily form an inhomogeneous texture, resulting in anisotropic mechanical properties and poor formability. However, few studies have been carried out on the bulk texture investigation at different areas of as-extruded Mg alloy sheets, especially the Mg alloys with different alloying elements. In this work, the effect of Al on the bulk texture and mechanical properties at different areas for three wide Mg-Al-Zn alloy sheets with different Al contents (Mg-3Al-0.

Simple transabdominal minimally invasive direct coronary artery bypass surgery with right gastroepiploic artery.

For three patients with isolated right coronary artery disease who had drug resistance and were intolerant to interventional therapy, simple transabdominal small incision bypass grafting of the right gastroepiploic artery and the posterior descending branch of the right coronary artery was conducted without cardiopulmonary. All three patients were discharged smoothly without complications, and were followed up for three months, during which time the myocardial bridges were unobstructed and the cardiac functions were good. The surgery needs no thoracotomy and the injury is small, and avoids influences of sternum and pericardium adhesion on other cardiac surgery in the future.

Copper(I)-Catalyzed Asymmetric Vinylogous Aldol-Type Reaction of Allylazaarenes.

A vinylogous aldol-type reaction of allylazaarenes and aldehydes is disclosed that affords a series of chiral γ-hydroxyl-α,β-unsaturated azaarenes in moderate to excellent yields with high to excellent regio- and enantioselectivities. With (R,R )-TANIAPHOS and (R,R)-QUINOXP* as the ligand, the carbon-carbon double bond in the products is generated in (E)-form. With (R)-DTBM-SEGPHOS as the ligand, (Z)-form carbon-carbon double bond is formed in the major product.

A novel amphiphilic oligopeptide induced the intrafibrillar mineralisation via interacting with collagen and minerals.

Mineralised collagen fibrils constitute the basic building blocks of bone, dentin and cementum. Noncollagenous proteins (NCPs) that are indispensable for collagen biomineralisation are not commercially available, and the mechanism of intrafibrillar mineralisation remains debatable. Herein, synthetic biomimetic molecules are regarded as alternative candidates for NCPs, and more convenient in revealing the mechanism of intrafibrillar mineralisation in vitro.

[Physiological responses of five plants in northwest China arid area under drought stress].

Effects of drought stress on photosynthetic characteristics, water status, physiological and biochemical indexes were studied in five arid area plants in northwest China, including Potentilla fruticosa, Lycium ruthenicum, Caryopteris mongholica, Caragana korshinskii and Hedysarum scoparium, using pot experiments. The results showed that with the prolongation of drought stress, the water conservation capacity of leaves totally increased in above five plants, the leaf relative water content rose first and then fell, and the relative chlorophyll content and chlorophyll fluorescence parameters decreased to some extent. Overall, the photosynthetic system of H.

Synthesis of oxazolines from amides via palladium-catalyzed functionalization of unactivated C(sp(3))-H bond.

A complementary method that enables the expeditious synthesis of oxazolines from amides via Pd-catalyzed C(sp(3))-H functionalization has been described. Preliminary studies indicate that the reaction might go through a chlorination/nucleophilic cyclization sequence, and the high efficiency of this sequence is enhanced by the in situ cyclative capture of the chlorinated intermediate. The resulting oxazolines can be further converted into the corresponding β-amino alcohols without chromatography.

N-(4,5-Diaza-9H-fluoren-9-yl-idene)-4-meth-oxy-aniline.

In the title compound, C(18)H(13)N(3)O, the diaza-fluorene ring system is almost coplanar (r.m.s.

4,5-Diaza-9H-fluoren-9-imine.

In the title compound, C(11)H(7)N(3), the diaza-fluorene rings are almost coplanar with an r.m.s.

N-(4,5-Diaza-fluoren-9-yl-idene)-4-methyl-aniline.

In the mol-ecule of the title compound, C(18)H(13)N(3), the 4,5-diaza-fluorenyl-idene unit is nearly planar and is oriented at a dihedral angle of 66.31 (1)° with respect to the benzene ring. In the crystal structure, mol-ecules are stacked regularly along the c axis.

N-(4,5-Diaza-fluoren-9-yl-idene)aniline.

In the mol-ecule of the title compound, C(17)H(11)N(3), the 4,5-diaza-fluorenyl-idene unit is nearly planar and is oriented with respect to the phenyl ring at a dihedral angle of 75.75 (3)°. In the crystal structure, the mol-ecules are aligned in the [100] direction in such a way that neighbouring 4,5-diaza-fluorenyl-idene planes face each other in an anti-parallel fashion.