Publications by authors named "Si-Qi Sheng"
Eur J Pharmacol
September 2022
Article Synopsis
- Long noncoding RNA-Myosin heavy chain associated RNA transcript (LncRNA-MHRT) has a role in preventing pathological cardiac hypertrophy, although its exact mechanism is not fully understood.
- The study investigates how MHRT affects protein modification, specifically looking into the SUMOylation of proteins like SIRT1, which is linked to heart function.
- Results indicate that MHRT not only improves heart function by reducing cardiac hypertrophy but may also offer a promising therapeutic target through its regulation of protein SUMOylation pathways.
