Poly(vinyl alcohol)/ZSM-5 zeolite mixed matrix membranes for pervaporation dehydration of ethanol and n-propanol.

In this study, mixed matrix membranes (MMMs) composed of poly(vinyl alcohol) (PVA) and porous ZSM-5 zeolite are thoroughly investigated for concentrating alcohols of ethanol and n-propanol via dewatering pervaporation. The effects of the zeolite content (10-30 wt.%), feed composition (5-30 wt.

Efficacy of dupilumab plus topical corticosteroids in children with atopic dermatitis: A meta-analysis of randomized controlled trials.

Introduction: Children with atopic dermatitis (AD) bear a significant burden of illness that adversely affects their quality of life.

Objective: To determine the efficacy of dupilumab and topical corticosteroids for the treatment of pediatric AD.

Methods: A comprehensive literature search was conducted using three prominent databases: Web of Science, PubMed, and Embase.

The ctDNA-based postoperative molecular residual disease status in different subtypes of early-stage breast cancer.

Background: Breast cancer is a highly heterogeneous disease. Early-stage, non-metastatic breast cancer is considered curable after definitive treatment. Early detection of tumor recurrence and metastasis through sensitive biomarkers is helpful for guiding clinical decision-making and early intervention in second-line treatment, which could improve patient prognosis and survival.

Olmesartan Improves Hepatic Sinusoidal Remodeling in Mice with Carbon Tetrachloride-Induced Liver Fibrosis.

Aim: In mice with liver fibrosis produced by carbon tetrachloride (CCl), the effects of olmesartan on intrahepatic angiogenesis and sinusoidal remodeling will be evaluated.

Methods: By injecting CCl into the peritoneal cavity, we established a mouse model of liver fibrosis. Using Sirius red and Masson trichrome staining, the extent of liver fibrosis in the animals was determined.

Trans-cinnamaldehyde suppresses microtubule detyrosination and alleviates cardiac hypertrophy.

Background: Trans-cinnamaldehyde (TCA) is a main compound of Cinnamomum cassia, used in traditional Chinese medicine to treat many ailments. Increasing evidence has demonstrated the therapeutic effects of TCA in cardiovascular diseases.

Purpose: The present study aimed to determine whether TCA exerts antihypertrophic effects in vitro and in vivo and to elucidate the underlying mechanisms of these effects.

Stachydrine hydrochloride alleviates pressure overload-induced heart failure and calcium mishandling on mice.

Ethnopharmacological Relevance: Traditional Chinese medicine Leonurus japonicus Houtt. has a long history in the treatment of cardiovascular diseases. Stachydrine hydrochloride, the main bioactive ingredient extracted from Leonurus japonicus Houtt.

Carvedilol attenuates carbon tetrachloride-induced liver fibrosis and hepatic sinusoidal capillarization in mice.

Aim: To investigate the effect of carvedilol on liver fibrosis and hepatic sinusoidal capillarization in mice with carbon tetrachloride (CCl)-induced fibrosis.

Methods: A liver fibrosis mouse model was induced by intraperitoneal CCl injection for 8 weeks. The mice were divided into five experimental groups: the normal group, the oil group, the CCl group, the CCl+carvedilol (5 mg/kg/d) group, and the CCl+carvedilol (10 mg/kg/d) group.