Publications by authors named "Si-Min Pan"
J Ethnopharmacol
January 2024
Article Synopsis
- Ulcerative colitis (UC) is a significant inflammatory bowel disease affecting the colon, and traditional remedies like Baitouweng decoction (BD) are being re-evaluated for their medicinal properties despite limited understanding of their mechanisms.
- This study assesses the impact of BD on autophagy in DSS-induced colitis mice, focusing on its role in enhancing the colonic barrier through the AMPK/mTOR signaling pathway.
- Results show that BD effectively alleviates colitis symptoms by improving body weight and colon length, reducing inflammation, and enhancing the intestinal barrier function.
Palliat Med Rep
August 2022
Article Synopsis
- The study focused on translating and validating a specific health scale, the Short Health Scale (SHS), designed to assess the quality of life (QoL) in patients with inflammatory bowel disease (IBD) in mainland China.
- The researchers used established methods like translation, back-translation, and various reliability and validity tests, involving 112 IBD patients to ensure the scale was effective.
- Results showed that the SHS had strong reliability (Cronbach's alpha of 0.90) and was able to differentiate QoL based on symptom severity, confirming its suitability for IBD patients in the Chinese context.*
