[Value of SOX1 and PAX1 Gene Methylation Detection in Secondary Triage of High-Grade Cervical Lesions].

Objective To evaluate the value of SOX1 and PAX1 gene methylation detection in the secondary triage of high-grade cervical lesions.Methods Exfoliated cervical cells were collected from 122 patients tested positive for human papilloma virus (HPV) and subjected to thin-prep cytologic test (TCT) and SOX1/PAX1 gene methylation tests.Results The HPV test combined with TCT showed the sensitivity of 95.

[Clinical study of electroacupuncture therapy on postoperative rehabilitation of patients with knee fractures].

Objective: To investigate the effect of electroacupuncture therapy on postoperative rehabilitation training of patients with knee fractures.

Methods: Patients with knee fractures from July 2020 to July 2021 were randomly assigned to either the experimental group or a control group according to the double-blind principle. Both groups were given surgical treatment and postoperative conventional rehabilitation training.

[Main Chemical Components in Atmospheric Precipitation and Their Sources in Xi'an].

In order to understand the current status of main chemical components of atmospheric precipitation in Xi'an, the pH, electrical conductivity, mass concentration of water-soluble ions and heavy metals, wet deposition fluxes, and their sources in precipitation samples in urban and suburban areas of Xi'an in 2019 were studied. The results showed that the pH, conductivity, water-soluble ions, and heavy metals in precipitation in Xi'an in winter were higher than those in other seasons. The main water-soluble ions in precipitation were Ca, NH, SO, and NO, and the sum of these ions accounted for (88.

Combined computational analysis and cytology show limited depth osteogenic effect on bone defects in negative pressure wound therapy.

The treatment of bone defects remains a clinical challenge. The effect of negative pressure wound therapy (NPWT) on osteogenesis in bone defects has been recognized; however, bone marrow fluid dynamics under negative pressure (NP) remain unknown. In this study, we aimed to examine the marrow fluid mechanics within trabeculae by computational fluid dynamics (CFD), and to verify osteogenic gene expression, osteogenic differentiation to investigate the osteogenic depth under NP.

Randomized Trial of First-Line Tyrosine Kinase Inhibitor With or Without Radiotherapy for Synchronous Oligometastatic EGFR-Mutated Non-Small Cell Lung Cancer.

Background: Adding radiotherapy (RT) to systemic therapy improves progression-free survival (PFS) and overall survival (OS) in oligometastatic non-small cell lung cancer (NSCLC). Whether these findings translate to epidermal growth factor receptor (EGFR)-mutated NSCLC remains unknown. The SINDAS trial (NCT02893332) evaluated first-line tyrosine kinase inhibitor (TKI) therapy for EGFR-mutated synchronous oligometastatic NSCLC and randomized to upfront RT vs no RT; we now report the prespecified interim analysis at 68% accrual.

Association of serum uric acid with biventricular myocardial dysfunction in patients with type 2 diabetes mellitus.

Background And Aims: Increased serum uric acid (SUA) is common in type 2 diabetes mellitus (T2DM) and is associated with left ventricular (LV) myocardial dysfunction. Nonetheless the association of SUA with right ventricular (RV) function in T2DM has not been studied. This study aimed to investigate the association of SUA with biventricular myocardial function in patients with T2DM.

Single-cell profiling lights different cell trajectories in plants.

The molecular mechanism of the maintenance and differentiation of plant stem cells is an eternal theme in studies on plant growth and development. Recent advances in single-cell RNA sequencing (scRNA-seq) methods have completely changed the understanding of cell heterogeneity and cell function, allowing research precision to identify the differentiation trajectory of stem cells maintained and differentiated at the cellular level. This review aimed to mainly discuss the novel insights provided by scRNA-seq for the maintenance and initiation of plant stem cells, cell differentiation, cell response to environmental changes, and improvement strategies for scRNA-seq.

Cytokinins as central regulators during plant growth and stress response.

Cytokinins are a class of phytohormone that participate in the regulation of the plant growth, development, and stress response. In this review, the potential regulating mechanism during plant growth and stress response are discussed. Cytokinins are a class of phytohormone that participate in the regulation of plant growth, physiological activities, and yield.

SERS studies on normal epithelial and cancer cells derived from clinical breast cancer specimens.

Surface-enhanced Raman scattering (SERS) spectroscopy of single-cell suspensions obtained from fresh specimens of breast cancer tissue and normal breast tissue by mechanical enzymatic digestion was obtained and analysed, which is different from most Raman studies using breast cancer cell lines. Random forest classification was implemented to develop effective diagnostic algorithms for the classification of SERS of different typed cells. We first examined the SERS spectra of the primary breast cancer single cell and normal epithelial single cell obtained by flow sorting cytometry due to their biomarkers of CD326+/CD45-.

Genetic differentiation of population based on mtDNA COII gene.

mtDNA COII gene sequences were identified and analyzed using different types of software, namely, MEGA5.0, DNAMAN, and DnaSP5.0 in four Chinese provinces, namely, Sichuan, Zhejiang, Guizhou and Shanghai.

Metal and graphene hybrid metasurface designed ultra-wideband terahertz absorbers with polarization and incident angle insensitivity.

Terahertz electromagnetic (EM) wave absorbers are vital in photonics, however, they suffer from limited bandwidth. A new approach for ultra-wideband (UWB) terahertz absorber design is proposed with metal and graphene metasurfaces. The UWB characteristics are owing to three factors: (1) the metal metasurface boosts the surface plasmon-polaritons (SPPs) of the graphene metasurface which leads to confined field enhancement, (2) the merging and interaction of the resonances of the metal and graphene metasurfaces, and (3) the multiple reflections and superpositions between the metasurfaces and the gold layer.

Multi-functional Device with Switchable Functions of Absorption and Polarization Conversion at Terahertz Range.

Terahertz electromagnetic (EM) wave components usually have a single function, such as they can only convert the polarization state of an incident wave or absorb the incident energy, which would be a limitation for their applications. To make a breakthrough, a multi-functional device (MFD) is proposed in this paper, and it is capable of switching between absorption mode and polarization conversion mode. The device has a low-profile and simple structure, and it is constructed by graphene-based absorbing metasurface (AM) and gold-based polarization conversion metasurface (PCM).

Resonance-Based Reflector and Its Application in Unidirectional Antenna with Low-Profile and Broadband Characteristics for Wireless Applications.

In this research, the novel concept of a resonance-based reflector (RBR) was proposed, and a ring-shaped RBR was utilized to design a unidirectional antenna with low-profile and broadband characteristics. Research found the ring operates as two half-wavelength (/2) resonators. Then, the resonance effect transforms the reflection phase of the ring RBR, and achieves a reflection phase of 0° < < 180° in a wide frequency range above the resonance.

RF Spectrum Sensing Based on an Overdamped Nonlinear Oscillator Ring for Cognitive Radios.

Existing spectrum-sensing techniques for cognitive radios require an analog-to-digital converter (ADC) to work at high dynamic range and a high sampling rate, resulting in high cost. Therefore, in this paper, a spectrum-sensing method based on a unidirectionally coupled, overdamped nonlinear oscillator ring is proposed. First, the numerical model of such a system is established based on the circuit of the nonlinear oscillator.

Generalized Poincaré sphere.

We present a generalized Poincaré sphere (G sphere) and generalized Stokes parameters (G parameters), as a geometric representation, which unifies the descriptors of a variety of vector fields. Unlike the standard Poincaré sphere, the radial dimension in the G sphere is not used to describe the partially polarized field. The G sphere is constructed by extending the basic Jones vector bases to the general vector bases with the continuously changeable ellipticity (spin angular momentum, SAM) and the higher dimensional orbital angular momentum (OAM).

Reversion of left ventricle remodeling in spontaneously hypertensive rats by valsartan is associated with the inhibition of caspase-3, -8 and -9 activities.

The development of hypertension is closely associated with cardiac hypertrophy and apoptosis, and caspase-3, -8 and -9 are key enzymes of apoptosis. The aim of the present study was to evaluate the effects of valsartan on left ventricle hypertrophy and myocardial apoptosis in spontaneously hypertensive rats (SHRs) and to explore the mechanisms for valsartan against apoptosis. A total of 15 SHRs (16 weeks old) were randomly divided into two groups.

A 90° fair circular waveguide bend.

We propose a synthesis method to design a 90° bent fair circular waveguide TE01 mode transition based on the non-uniform rational B-spline technique. The transition by this method has advantages of small geometry, high transmission with wide band and high profile fairness. An example of design of such a transition is presented.

Elliptic-symmetry vector optical fields.

We present in principle and demonstrate experimentally a new kind of vector fields: elliptic-symmetry vector optical fields. This is a significant development in vector fields, as this breaks the cylindrical symmetry and enriches the family of vector fields. Due to the presence of an additional degrees of freedom, which is the interval between the foci in the elliptic coordinate system, the elliptic-symmetry vector fields are more flexible than the cylindrical vector fields for controlling the spatial structure of polarization and for engineering the focusing fields.

Vector optical fields with bipolar symmetry of linear polarization.

We focus on a new kind of vector optical field with bipolar symmetry of linear polarization instead of cylindrical and elliptical symmetries, enriching members of family of vector optical fields. We design theoretically and generate experimentally the demanded vector optical fields and then explore some novel tightly focusing properties. The geometric configurations of states of polarization provide additional degrees of freedom assisting in engineering the field distribution at the focus to the specific applications such as lithography, optical trapping, and material processing.

Vector optical fields with polarization distributions similar to electric and magnetic field lines.

We present, design and generate a new kind of vector optical fields with linear polarization distributions modeling to electric and magnetic field lines. The geometric configurations of "electric charges" and "magnetic charges" can engineer the spatial structure and symmetry of polarizations of vector optical field, providing additional degrees of freedom assisting in controlling the field symmetry at the focus and allowing engineering of the field distribution at the focus to the specific applications.

Taming the collapse of optical fields.

Field collapse, which occurs in various nonlinear systems, has attracted much attention, owing to its universality, complexity, and applicability. A great challenge and expectation is to achieve the controllable and designable collapsing pattern. Here we predict theoretically and demonstrate experimentally the novel collapsing behaviors of the vector optical fields in a self-focusing Kerr medium.

Resveratrol Inhibits respiratory syncytial virus-induced IL-6 production, decreases viral replication, and downregulates TRIF expression in airway epithelial cells.

Respiratory syncytial virus (RSV) is the most common pathogen responsible for lower respiratory diseases in children. So far, there is no effective treatment or preventative vaccine available for RSV infection, although ribavirin and dexamethasone are commonly prescribed. Resveratrol has been shown to inhibit the replication of several other viruses, thus the effect of resveratrol on RSV-induced inflammatory mediators in 9HTEo cell cultures was evaluated, and possible mechanisms of action were explored and compared with dexamethasone and ribavirin.