Baicalin administration could rescue high glucose-induced craniofacial skeleton malformation by regulating neural crest development.

Hyperglycemia in pregnancy can increase the risk of congenital disorders, but little is known about craniofacial skeleton malformation and its corresponding medication. Our study first used meta-analysis to review the previous findings. Second, baicalin, an antioxidant, was chosen to counteract high glucose-induced craniofacial skeleton malformation.

A novel hybrid scan approach enabling the ion-mobility separation and the alternate data-dependent and data-independent acquisitions (HDDIDDA): Its combination with off-line two-dimensional liquid chromatography for comprehensively characterizing the multicomponents from Compound Danshen Dripping Pill.

Data-dependent acquisition (DDA) and data-independent acquisition (DIA)-based MS strategies are extensively applied in metabolites characterization. DDA gives accurate MS information, but receives low coverage, while DIA covers the entire mass range, but the precursor-product ions matching often yields false positives. Currently available MS scan approaches rarely integrate DIA and DDA within a duty circle.

[Study on the response of middle and trace elements in Humulus scandens leaves to atmospheric reactive nitrogen with ICP-AES].

Based on field measurements, the effects of atmospheric reactive nitrogen (ARN) on the middle/trace element concentrations in the leaves of wild plant humulus scandens were analyzed. Leaves of H. scandens were collected from six sites around Beijing in the North China Plain, and the concentrations of Ca, Mg, S, Fe, Mn, Cu, Zn, B, and Na in the leaves were determined with inductively coupled plasma atomic emission spectrometry (ICP-AES).