Synopsis of recent research by authors named "Si-Jie Dai"
- Si-Jie Dai's recent research focuses on exploring innovative therapeutic agents for epilepsy, specifically targeting the role of HMGB1 in seizure progression.
- The study published in "Acta Pharmacol Sin" demonstrates that Inflachromene significantly reduces the severity of seizures in mouse models of epilepsy by inhibiting the translocation of HMGB1, a protein implicated in the regulation of neural excitability.
- Findings suggest that the modulation of HMGB1 could represent a novel approach to improving the efficacy of anti-seizure treatments, addressing current limitations in seizure management.
