Publications by authors named "Si-Jian Li"
Article Synopsis
- Recent research identifies Fol-milR1, a small RNA from the fungus Fusarium oxysporum f. sp. lycopersici, as a key player in affecting tomato plant resistance during infections.
- The study found that knockout strains lacking Fol-milR1 showed reduced virulence on susceptible tomato plants, while overexpressing strains displayed increased virulence against resistant varieties.
- A targeted gene, SlyFRG4, crucial for resistance, is regulated by Fol-milR1 and interacts with the host's immune response, showing how this fungal RNA can suppress tomato immunity to facilitate infection.
An alternative stapling strategy is described herein using Fmoc-solid phase peptide synthesis (SPPS) that employed pre-prepared diaminodiacid building blocks to introduce all-hydrocarbon staples into peptides by on-resin cyclization. Compared to unstapled native peptides, diaminodiacid-based stapled peptides exhibited an increased α-helicity ratio and stability toward protease. Moreover, the linkage length was found to affect the bioactivity of the peptides and their ability to inhibit the Wnt pathway.
View Article and Find Full Text PDF[Psychological factors of adopting and maintaining physical activity for individuals with hypertension in a community].
Zhonghua Liu Xing Bing Xue Za Zhi
August 2012
Objective: To examine the impact of psychosocial factors on physical activity, so as to provide guidance for the development of an effective physical activity intervention program for individuals with hypertension.
Methods: This study used a baseline data from an intervention study on regular physical activity among hypertensive individuals. A multi-stage, stratified random sampling was utilized and finally 12 communities from 6 urban districts were chosen.
Interactions between inflammatory and oxidative stress in preeclampsia.
Hypertens Pregnancy
February 2009
Objective: Oxidative stress and a generalized inflammatory state are features of preeclampsia (PE). The objective of this study was to compare the levels of products of inflammatory reaction and oxidative stress markers in patients with PE, and to determine the relationship between oxidative stress and inflammation in PE.
Methods: Plasma concentrations of high-sensitive C-reactive protein (hs-CRP), interleukin (IL)-6, tumor necrosis factor-alpha (TNF-alpha), malondialdehyde (MDA), and 8-isoprostane were measured in 53 women with PE and 20 age- and BMI-matched normotensive women.
Purpose: Considerable interest has been focused on angiogenic factors and angiogenic imbalance in the field of pre-eclampsia (PE), owing to its gaining role in the development of PE. This study was addressed to investigate the associations of sFlt-1-to-PlGF plasma ratios with oxidative stress assessed by the level of 8-isoprostane, and inflammation measured by the level of high-sensitive C-reactive protein (hs-CRP), and adipocytokines.
Methods: A total of 83 patients with PE including 47 mild PE (MPE) and 36 severe PE (SPE) and 50 age-matched normotensive subjects in the third trimester of pregnancy were examined.