To evaluate the distribution of the transforming growth factor-beta induced (TGFBI) corneal dystrophies in a multi-ethnic population in Singapore, and to present the different phenotypes with the same genotype. This study included 32 patients. Slit lamp biomicroscopy was performed for each patient to determine the disease phenotype.
View Article and Find Full Text PDFPurpose: The aim of the study is to examine the baseline intraocular pressure (IOP) and its changes after performing a water drinking test (WDT) in patients with unilateral hemifacial spasm (HFS).
Patients And Methods: In this prospective observational study, patients aged 21 years and above diagnosed with unilateral HFS were recruited from the Singapore National Eye Centre between January 2015 and August 2016. The unaffected eye of each patient served as a matched control.
Non-infectious anterior uveitis (AU) is a potentially sight threatening inflammatory condition. The current gold standard for treatment is topical steroids, but low ocular bioavailability and compliance issues with the intensive dosing regimen limit the efficacy of this treatment. Liposomes as a drug delivery system may help to overcome these problems.
View Article and Find Full Text PDFPurpose: To report a case of unilateral maculopathy associated with acute Zika virus infection.
Methods: Observational case report of one patient.
Results: A 22-year-old man presented with acute blurring of vision 10 days after symptoms of Zika virus infection.
Purpose: To describe 12-month changes in choroidal thickness after anti-vascular endothelial growth factor (anti-VEGF) therapy for typical age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV).
Design: Prospective, consecutive, noninterventional, longitudinal case series.
Methods: This study included patients with typical AMD and PCV who received anti-VEGF therapy over a 12-month period.