Synopsis of recent research by authors named "Si Bei Poh"
- Si Bei Poh's research predominantly focuses on the development of N-heterocyclic carbene (NHC)-catalyzed methods for enantioselective transformations, emphasizing kinetic resolution and atroposelective acylation of various alcohols and amines, which provide access to valuable chiral compounds with high enantiopurity.
- Recent studies have demonstrated innovative catalytic strategies such as catalytic borrowing hydrogen, enabling economical and efficient one-pot syntheses of diverse enantiopure tetrahydropyridines and complex bridged biaryls, showcasing high levels of stereoselectivity and minimal waste.
- Poh's findings contribute significantly to the field of asymmetric synthesis, introducing novel methods for the practical access to axially chiral compounds that can be applied in drug delivery and other chemical applications, thereby overcoming challenges associated with traditional synthesis routes.
