[Quantitative relationship of renal blood flow with size and density of glomeruli in rat postnatal ontogenesis].

The aim of the study was to find the quantitative relationship of postnatal changes in the glomeruli anatomic structure with the blood flow in kidneys. Kidney development was studied in 4-, 12-, 30-, and 65-day-old Wistar rats. Diameters of glomerulus (Dgl, microm), afferent and efferent arterioles (Daf and Def), and the glomeruli density (Ngl, mm(-3)) were measured posthumously.

[Dynamics organ blood flow in rats in postnatal ontogenesis].

In the 4-, 13-, 30-, and 65- 90-day-old Wistar rats the voluminous blood flow rate was measured in liver, kidney, small intestine wall, and in the predominantly white gracilis muscle of femur. A LAKK-01 laser-Doppler flowmeter and its cutaneous (for kidney) and needle (for other organs) probes were used; they provided estimation of blood flow (per organ mass unit) to the tissue depth of about 1 mm. It has been found that the blood flow rates (per organ mass unit fall in liver, intestine, and even more in muscle, whereas increase in kidney, particularly for the first month of life.

[The glomerular apparatus and renal blood flow in rats during postnatal ontogenesis].

In anesthetized Wistar rats of the age of 4, 12, 30 and 65 days, the renal blood flow (RBF) with laser-Doppler flowmetry, diameter, number and density of glomeruli, diameter of afferent and efferent arterioles were measured. We found that during rat development the RBF increased 2.8-fold, the diameter of glomeruli--3.