Publications by authors named "Shymaa Abdullah Mohamed"
Article Synopsis
- Triple negative breast cancer (TNBC) is a highly aggressive cancer subtype with poor survival rates, prompting interest in less toxic metal-based therapies like copper complexes.
- This study investigates the effects of copper(I) nicotinate (CNC) on TNBC cell lines, focusing on its influence on the Notch1 signaling pathway and its potential to induce apoptotic cell death alongside the traditional drug doxorubicin (Doxo).
- While CNC demonstrated promising anti-cancer activities by modulating the Notch1 pathway differently depending on the cell type and dosage, these factors must be carefully considered for effective treatment strategies.
