IHC expression of AKT in different grades of epithelial dysplasia: An study.

Introduction: Akt, also known as protein kinase B, is a serine/threonine-specific protein-kinase which plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, transcription and cell migration. The activation of Akt is one of the most frequent alterations observed in human cancer and tumour cells. Akt regulates cellular survival and metabolism by binding and regulating many downstream effectors, e.

Dentinal translucency and width of cementum: predicting the age over 55 years in South Indian adults using extracted sectioned teeth.

The main intention of this article was to evaluate the reliability of root dentine translucency (RDT) and the width of cementum (CW) in indicating the age over 55 years in forensic and criminal investigations. 600 non-restored, single rooted teeth (300 males and 300 females) which were extracted for periodontal or orthodontic reasons were collected. Each tooth was sectioned longitudinally until the desired thickness (250 µm) was obtained.

Isolation, Characterization, and Drug Sensitivity of in Captive Sloth Bears (): Unnatural Habitat With Human Environment May Predispose Sloth Bears to Tuberculosis.

We describe the isolation, molecular characterization, and drug sensitivity of recovered from lung tissues of four rescued captive sloth bears () at Bannerghatta Biological Park (BBP), Bangalore, India. These bears had lived most of their life with humans in circus companies. They were rescued and housed in the Bear Rescue Center (BRC) of BBP.

Reliability of dentin translucency and incremental cemental lines in age estimation using light and stereomicroscopes: A comparative study.

Age estimation of the dead and human remains has been challenging in forensic medicine, both in mass disasters and criminal investigations. There are several approaches to accurately evaluate age, each with its own benefits and drawbacks. Dentine translucency (DT) and incremental cemental lines (ICL) have often been used for age estimation in living adults and unknown skeletal remains.

Immunohistochemical evaluation of myofibroblasts in odontogenic keratocyst, dentigerous cyst and different clinical variants of ameloblastoma: A comparative study.

Background: Odontogenic cysts and tumors exhibit varying degrees of aggressiveness in their biological behavior. Odontogenic keratocyst (OKC), dentigerous cyst (DC), ameloblastoma are most common odontogenic cysts and tumors to occur in the oral cavity. Myofibroblasts (MFs) in the connective tissue stroma participate in the matrix degradation process by secreting matrix metalloproteinase 2, transforming growth factor beta1 and may contribute to variation in their biological behavior.

An Ultrastructural Study on the Effect of High Temperatures on Teeth and Restorative Materials That Aids in the Identification of Human Remains.

Introduction: In most disasters, teeth are the only means of positive identification of an otherwise unrecognizable body, as there has been tremendous increase in the use of dental restorations that have different resistance to prolonged high temperature which is an important aid in identifying burned victims. Application of SEM/EDS in forensics was found useful in areas where there is a need for good imaging with high magnification combined with elemental analysis. The objective of this study was to analyze incineration effects on teeth and restorative materials using SEM/EDS.

Ameloblastic fibrosarcoma - A rarity?

Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic tumour classified by the WHO (1992) as an odontogenic sarcoma and defined as "a neoplasm with a similar structure to ameloblastic fibroma (AF) but in which the ectomesenchymal component shows the features of a sarcoma." The first report of AFS was published by Heath in 1887. AFS and related lesions are less frequently diagnosed than odontogenic carcinomas.

Extra Nasopharyngeal Angiofibroma Simulating a Mucocele: A New Location for the Rare Entity.

Angiofibromas are rare, benign, but locally aggressive vascular tumours which account for 0.05-0.5% of all head and neck neoplasms.

Evaluation of the Nature of Collagen Fibers in KCOT, Dentigerous Cyst and Ameloblastoma using Picrosirius Red Stain - A Comparative Study.

Background: Reciprocal interaction between dental epithelium and mesenchyme is thought to be crucial for normal odontogenesis. Thus, the mesenchymal influence of the fibrous capsules may play an important role in the maintenance of epithelial expression. Collagen is the major component of the extracellular matrix and possibly there is an alteration in the nature and structure of collagen in various pathological conditions.

Desmoplastic Ameloblastoma - An Unusual Presentation.

Ameloblastomas are the most common and represents a family of diseases with diverse biological behaviour and contribute to 11-18% of odontogenic epithelial neoplasms. Downstream it has been regarded as benign neoplasm with local aggressiveness. Desmoplastic ameloblastoma is the least frequent of all the variants of ameloblastoma and contribute to 4-5%.

+Ophitoxaemia and myocardial infarction--the issues during primary angioplasty: a review.

'The Big four' are the most poisonous snakes in India, and especially in Kerala. These include the cobra, the viper, the krait and the sea snake. Most of the poisonous snakebites in India occur in Kerala.

Phytochemical screening and antimicrobial activities of plant extract of Lantana camara.

Natural products continue to play an important role in the discovery and development of new pharmaceuticals. Several chemical compounds have been extracted and identified from its species known as Lantana camara (L .camara).

Nasopalatine duct cyst: report of a case with review of literature.

The nasopalatine duct cyst is the most common non-odontogenic developmental cysts. Nasopalatine duct cyst also termed as incisive canal cyst, arises from embryologic remnants of nasopalatine duct. Most of these cysts develop in the midline of anterior maxilla near the incisive foramen.

Overexpression of MDM2 protein in ameloblastomas as compared to adenomatoid odontogenic tumor.

Background: Recent studies on odontogenic tumors have identified various molecular alterations responsible for their development, and determination of epithelial proliferation is a useful means of investigating the differences in biologic behavior of these tumors. One such specific marker to identify proliferative activity and tumor aggressiveness by immunohistochemistry (IHC) is MDM2, 90-95 kDa protein.

Objective: This immunohistochemical study using MDM2 expression was undertaken to understand better the diverse biological activity of two groups of odontogenic tumors namely ameloblastoma and adenomatoid odontogenic tumor (AOT) based on their cell proliferation activity.

Ru (III) catalyzed oxidation of aliphatic ketones by N-bromosuccinimide in aqueous acetic acid: a kinetic study.

Kinetics of Ru (III) catalyzed oxidation of aliphatic ketones such as acetone, ethyl methyl ketone, diethyl ketone, iso-butylmethyl ketone by N-bromosuccinimide in the presence of Hg(II) acetate have been studied in aqueous acid medium. The order of [N-bromosuccinimide] was found to be zero both in catalyzed as well as uncatalyzed reactions. However, the order of [ketone] changed from unity to a fractional one in the presence of Ru (III).

Hydrogen-bonded sheets in 2-(2-aminophenyl)-1H-benzimidazol-3-ium dihydrogen phosphate.

The title salt, C(13)H(12)N(3)(+).H(2)PO(4)(-), contains a nonplanar 2-(2-aminophenyl)-1H-benzimidazol-3-ium cation and two different dihydrogen phosphate anions, both situated on twofold rotation axes in the space group C2. The anions are linked by O-H.