The relationship among thromboelastography, hemostatic variables, and bleeding after cardiopulmonary bypass surgery in children.

Background: Mediastinal bleeding is common after pediatric cardiopulmonary bypass (CPB) surgery. Thromboelastography (TEG) may predict bleeding and provide insight into likely mechanisms. We aimed to (a) compare perioperative temporal profiles of TEG and laboratory hemostatic variables between patients with significant hemorrhage (BLEED) and those without (CONTROL), (b) investigate the relationship between TEG variables and routine hemostatic variables, and (c) develop a model for prediction of bleeding.

Retrospective evaluation of a paediatric intensivist-led flexible bronchoscopy service.

Objective: To demonstrate the diagnostic yield, therapeutic role and safety of flexible bronchoscopy via an intensivist-led service in critically ill children.

Design: Retrospective chart review.

Setting: Regional paediatric intensive care unit.