Publications by authors named "Shweta Walvekar"
Neuroinflammation is an inflammatory response in any part of the central nervous system triggered by the activation of microglia and astrocytes to produce proinflammatory cytokines in the brain. However, overproduction of proinflammatory cytokines further contributes to the development of neurodegenerative disorders. Red seaweed, is a predominant carrageenophyte commercially cultivated in Semporna, Sabah, Malaysia.
View Article and Find Full Text PDFNanomedicine has the potential in enhancing the efficacy and bioavailability of anti-infective agents. Here we determined whether conjugation of the Malaysian cultivated seaweed Kappaphycus alvarezii with silver-conjugated nanoparticles enhanced anti-acanthamoebic properties. Silver-conjugated K.
View Article and Find Full Text PDFArticle Synopsis
- Acanthamoeba spp. are opportunistic parasites found in nature that can cause serious infections in the eye, skin, and central nervous system, with current treatments showing limited efficacy.
- The review emphasizes the potential of azole compounds, which inhibit ergosterol biosynthesis—a crucial component for both Acanthamoeba and fungi—to effectively target and eliminate Acanthamoeba infections.
- Additionally, the incorporation of azoles into nanoparticles via advanced nanotechnology can enhance drug delivery and effectiveness, offering a novel strategy for treating these infections.