Unlabelled: FRAX scores were significantly higher in patients admitted with fragility fractures than controls and can be useful in choosing the right patients for bone density testing, thus using of an expensive test judiciously.
Purpose: This study was planned to compare the FRAX scores for the risk for major osteoporotic fracture (FRAX-MOF) and hip fracture (FRAX-HF) in patients with fragility fractures (cases) and those admitted for other indications (controls) in the orthopedic ward in our institute.
Methods: Historical and anthropometric data were prospectively recorded from 500 consecutive patients admitted in the orthopedic ward in in Medanta, the Medicity, Gurgaon, India.
There is burgeoning interest among supramolecular chemists to develop novel molecular systems to detect biogenic amines and bio-thiols in aqueous and non-aqueous media due to their potential role in biological processes. Biogenic amines are biologically important targets because of their involvement in the energy metabolism of human biological systems and their requirement is met through food and nutrition. However, the increasing instances of serious health problems due to food toxicity have raised the quality of food nowadays.
View Article and Find Full Text PDFA tetrapodal receptor was synthesized and was processed into fluorescent organic nanoparticles (FONs) for determination of important analytes in aqueous medium. The receptor was fully characterized using characterization techniques. Recognition behavior of FONs towards different metal ions was investigated with fluorescence spectroscopy, amongst them Fe ions showed quenching behavior in the emission spectra.
View Article and Find Full Text PDFThis work reports a label-free, ultrasensitive, and selective optical chemosensory system for trace level detection of selenite (SeO), the most toxic form of selenium, in water. The probe, i.e.
View Article and Find Full Text PDFA chemical sensor based on p-tert butyl calix[4]arene has been synthesized and characterized using an assortment of spectroscopic techniques such as (1)H NMR, (13)C NMR, and elemental analysis. For sensor application, organic nanoparticles (N1) of 1 have been primed by implementing re-precipitation technique, which were further employed for preparing organic-inorganic hybrid (H1) by decorating N1 with gold nanoparticles. Both N1 and H1 were characterized using UV-visible, fluorescence, and DLS studies.
View Article and Find Full Text PDFObjective: To study the effect of octreotide therapy on endometriotic lesions in a patient with coexisting endometriosis and acromegaly.
Intervention Patient: A 34-year-old female was diagnosed with acromegaly and coexisting endometriosis. Post-surgical resection of the tumor, patient was initiated on octreotide therapy.
Indian J Endocrinol Metab
May 2013
Adrenal histoplasmosis is an uncommon cause for adrenal insufficiency. The duration of treatment for adrenal histoplasmosis is not clear. Existing treatment regimens advocate antifungals given for periods ranging from 6 months to 2 years.
View Article and Find Full Text PDFIndian J Endocrinol Metab
May 2012
Objective: Octreotide, a long-acting synthetic somatostatin analog, has been widely used for ac-romegalic patients. Gastrointestinal (GI) side effects and gall stones are predominant side effects. We report incidence of gall stones in our cohort of acromegalic patients treated with octreotide therapy.
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