Sensitivity and specificity of the uniform field electroretinogram in glaucoma detection in comparison to the pattern electroretinogram.

Purpose: To determine the ability of the photopic negative response (PhNR) of the uniform field electroretinogram (UF-ERG) to identify early glaucomatous changes in comparison to the checkerboard and bar stimuli of the pattern electroretinogram (PERG).

Methods: Forty-nine glaucoma patients were classified into two groups: glaucoma-suspect (23 eyes) and early to moderate glaucoma (30 eyes), based on their clinical examination and the results of standard automated perimetry. Thirty patients (30 eyes) with intraocular pressures (IOP) of 21 mmHg or less, with no history of reported high IOP, were included as controls.

Effect of tobacco smoking on outcomes of trabeculectomy.

Purpose: To evaluate the effect of tobacco smoking on trabeculectomy outcomes.

Methods: Charts of patients with glaucoma who underwent trabeculectomy performed by a single surgeon between 2007 and 2016 were retrospectively reviewed. Charts were screened for a documented history of smoking status before surgery.

Randomized Trial on Illuminated-Microcatheter Circumferential Trabeculotomy Versus Conventional Trabeculotomy in Congenital Glaucoma.

Purpose: To compare 1-year outcomes of illuminated microcatheter-assisted circumferential trabeculotomy (IMCT) vs conventional partial trabeculotomy (CPT) for primary congenital glaucoma (PCG).

Design: Randomized clinical trial.

Methods: Forty eyes of 31 patients with unilateral or bilateral primary congenital glaucoma aged less than 2 years were randomized to undergo IMCT (20 eyes) or CPT (20 eyes).

Systemic Immunosuppression in High-Risk Penetrating Keratoplasty: A Systematic Review.

Cornea transplantation has a high success rate and typically only requires topical immunomodulation. However, in high-risk cases, systemic immunosuppression can be used. We conducted a systematic review on the efficacy and side effects of systemic immunosuppression for high-risk cornea transplantation.

Diurnal versus office-hour intraocular pressure fluctuation in primary adult onset glaucoma.

Purpose: To evaluates the role of measuring intraocular pressure (IOP) outside office-hour in primary adult onset glaucoma.

Methods: This retrospective study included 100 cases of primary adult onset glaucoma. IOP readings obtained with Goldmann applanation tonometry between 7 am and 10 pm were compared to office-hour readings.

Impact of initial topical medical therapy on short-term quality of life in newly diagnosed patients with primary glaucoma.

Purpose: To evaluate the impact of initial topical medical therapy on newly diagnosed glaucoma patients using the Indian Vision Function Questionnaire (IND-VFQ33).

Patients And Methods: The IND-VFQ33 was used to evaluate the quality of life (QoL) in 62 newly diagnosed patients with moderate to severe primary glaucoma and 60 healthy controls. IND-VFQ33 is a 33 item QoL assessment tool with three domains: General functioning, psychosocial impact and visual symptoms.

Test-retest variability of retinal nerve fiber layer thickness and macular ganglion cell-inner plexiform layer thickness measurements using spectral-domain optical coherence tomography.

Purpose: To evaluate the test-retest variability of spectral-domain optical coherence tomography (OCT) in measurement of retinal nerve fiber layer (RNFL) thickness and macular ganglion cell-inner plexiform layer (GCIPL) thickness.

Methods: A total of 65 eyes of healthy subjects were enrolled in this observational cross-sectional study. RNFL thickness and GCIPL thickness were measured using the repeat scan optic cube and macular cube protocol using Cirrus HD-OCT (software version 6.

Results of cataract surgery and plasma ablation posterior capsulotomy in anterior persistent hyperplastic primary vitreous.

Purpose: To report the feasibility and outcome of lens aspiration, and Fugo blade-assisted capsulotomy and anterior vitrectomy in eyes with anterior persistent hyperplastic primary vitreous (PHPV).

Materials And Methods: In this case series, 10 eyes of 10 patients with anterior PHPV underwent lens aspiration. The vascularized posterior capsule was cut with a Fugo blade (plasma knife) and removed with a vitrector.

Management of intra-Descemet membrane air bubble in big-bubble deep anterior lamellar keratoplasty.

Purpose: To report the recognition and management of intra-Descemet membrane air bubble (IDMA) as a complication of big-bubble deep anterior lamellar keratoplasty (DALK).

Methods: IDMA was present intraoperatively in 8 eyes after DALK. Indications for surgery were healed keratitis (n = 4), macular dystrophy (n = 2), and keratoconus (n = 2).

Test retest variability of TonoPen AVIA.

The study was conducted to evaluate the intra-session repeatability of Tonopen AVIA (TPA). 180 eyes of 180 patients (50 eyes with glaucoma, 130 eyes of controls) were recruited for this observational study. The mean age of patients enrolled in the study was 43.

Prevalence of diabetes mellitus and hypertension among Indian glaucoma patients and evaluation of systemic therapy.

To study the prevalence and systemic control and evaluate the adequacy of therapy of diabetes mellitus (DM) and hypertension (HT) in glaucoma patients visiting a tertiary care eye facility at a university hospital. Consecutive cases with primary open-angle glaucoma (POAG) or primary angle-closure glaucoma (PACG) attending the outpatient services were evaluated for the presence of DM and HT and any systemic/ocular medications being taken were recorded. Of 615 glaucoma cases evaluated, 281 (45.

Caregiver burden assessment in primary congenital glaucoma.

Purpose: To assess the magnitude of caregiver burden and depression in primary caregivers of patients with primary congenital glaucoma.

Methods: Fifty-five primary caregivers of children diagnosed with primary congenital glaucoma were evaluated. The magnitude of burden on caregivers was assessed using a Caregiver Burden Questionnaire (CBQ).

Outcomes of femtosecond laser cataract surgery with a diffractive multifocal intraocular lens.

Purpose: To report the visual and refractive outcomes in an initial series of eyes undergoing femtosecond laser cataract surgery with implantation of a diffractive multi-focal intraocular lens (IOL).

Methods: The first 61 consecutive eyes undergoing femtosecond laser cataract surgery and ReSTOR (Alcon Laboratories Inc) +3.00-diopter (D) add IOL implantation between May and July 2011 were enrolled in the study (LCS group).

Surgical outcomes and safety of femtosecond laser cataract surgery: a prospective study of 1500 consecutive cases.

Objective: To report the surgical outcomes and safety of femtosecond (FS) laser cataract surgery (LCS) with greater surgeon experience, modified techniques, and improved technology.

Design: Prospective, interventional case series.

Participants: Fifteen hundred consecutive eyes undergoing FS laser cataract and refractive lens exchange surgery in a single group private practice.

Femtosecond cataract surgery: transitioning to laser cataract.

Purpose Of Review: The introduction of the femtosecond laser to the field of cataract surgery offers many potential benefits. The femtosecond laser is able to perform three important steps in cataract surgery: capsulotomy, lens fragmentation and corneal incisions. Although evidence in support of its efficacy is accumulating, there is a surgical learning curve that needs to be addressed.

Intracorneal Ring Segment Reimplantation in Keratectasia.

Purpose: The objective of this study was to evaluate the safety and potential for visual improvement of replacing INTACS with Kerarings in patients with keratectasia.

Design: Retrospective case series.

Methods: A review of patients undergoing intracorneal segment exchange was conducted.

Trabeculectomy with combined use of subconjunctival collagen implant and low-dose mitomycin C.

Purpose: To evaluate outcomes of trabeculectomy with use of a subconjunctival biodegradable collagen implant (Ologen) combined with mitomycin C (MMC).

Methods: This retrospective study included 33 eyes of 24 patients with primary open-angle glaucoma who underwent fornix-based trabeculectomy with subconjunctival Ologen implant and MMC (0.1 mg/mL×1 min) between October 2008 and April 2010.

Femtosecond laser cataract surgery: technology and clinical practice.

The recent introduction of femtosecond lasers to cataract surgery has generated much interest among ophthalmologists around the world. Laser cataract surgery integrates high-resolution anterior segment imaging systems with a femtosecond laser, allowing key steps of the procedure, including the primary and side-port corneal incisions, the anterior capsulotomy and fragmentation of the lens nucleus, to be performed with computer-guided laser precision. There is emerging evidence of reduced phacoemulsification time, better wound architecture and a more stable refractive result with femtosecond cataract surgery, as well as reports documenting an initial learning curve.

A review of corneal melting following kerato-refractive surgery.

Corneal melting is a rare complication that may occur following a number of different types of surgery. Keratolysis may lead to scarring, irregular astigmatism, photophobia and decreased vision. This article reviews the incidence, pathophysiology and treatment of this condition in kerato-refractive surgery.

Recalcitrant Pseudomonas keratitis after epipolis laser-assisted in situ keratomileusis: case report and review of the literature.

We report a case of recalcitrant microbial keratitis after epipolis laser-assisted in situ keratomileusis (epi-LASIK) surgery caused by Pseudomonas aeruginosa and review the literature on resistant Pseudomonas keratitis after excimer laser surgery. Microbial keratitis occurred two weeks after epi-LASIK surgery and was resistant to fluoroquinolones, aminoglycosides and macrolides but sensitive to meropenem. The patient had total corneal melting and required therapeutic penetrating keratoplasty.

Prevalence of plateau iris configuration in primary angle closure glaucoma using ultrasound biomicroscopy in the Indian population.

Purpose: To report the prevalence of plateau iris in patients with primary angle closure glaucoma (PACG), in North India.

Materials And Methods: The patients with PACG, attending the glaucoma services at a tertiary care center in North India were included in the study. All patients had undergone Nd-YAG laser peripheral iridotomy at least four weeks prior to inclusion in the study.

Performance analysis of efforts towards promotion of corneal donation at a tertiary care trauma center in India.

Purpose: To identify the number of potential donors from trauma-related deaths and examine the extent of loss of opportunity at different levels for eye donation.

Methods: A retrospective review of the death records from the mortuary of Jai Prakash Narayan Apex Trauma Centre and National Eye Bank at All India Institute of Medical Sciences was conducted for the period between January 2008 and August 2009. All cases with trauma-related deaths were included in the study.

Comparative evaluation of Diaton and Goldmann applanation tonometers.

Aim: To evaluate the agreement between intra-ocular pressure (IOP) measurements with the Diaton and the Goldmann applanation tonometers (GAT).

Methods: In this cross-sectional observational study, a total of 196 eyes of 196 participants (66 patients with glaucoma, 130 healthy subjects) were included. IOP measurements were obtained from all patients using the Diaton and GAT.