Publications by authors named "Shvedov N"

Unlabelled: In otorhinolaryngology, the question of improving the tactics of early postoperative management in patients who have undergone surgery on the structures of the nasal cavity remains open. The timing of rehabilitation, the possible outcome of postoperative inflammation of the mucous membrane and the patient's ability to work depend on the choice of tactics. The nasal cavity differs from other anatomical areas in its rich blood supply, and therefore the problem of adequate hemostasis in the early stages after undergoing surgical treatment is still extremely relevant.

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Article Synopsis
  • Adhesion of the middle turbinate to the nasal cavity and synechia in the middle meatus are common causes for failed surgeries in chronic sinusitis patients.
  • The study introduces a new intranasal splint, designed with 3D modeling and made of biocompatible material, to prevent these complications post-surgery.
  • Initial testing with 20 volunteers showed the splint is safe, comfortable, and effective in preventing synechiae, but further research with a larger group is needed to confirm its clinical effectiveness.
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Article Synopsis
  • Treating severe chronic sinusitis with issues like pathological stretching is complex and can lead to serious complications.
  • The paper reviews existing research on this condition, covering factors that contribute to its development, how it progresses, and how it can be classified.
  • It also discusses modern surgical options for treatment, which may be done in one or two stages based on any aesthetic concerns arising from the condition.
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Neuron migration is a key phase of neurogenesis, critical for the assembly and function of neuronal circuits. In songbirds, this process continues throughout life, but how these newborn neurons disperse through the adult brain is unclear. We address this question using in vivo two-photon imaging in transgenic zebra finches that express GFP in young neurons and other cell types.

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Article Synopsis
  • Research highlights that the anatomical features of the hard palate are not well-documented, leading to complications in nasal surgeries like perforation during christotomy.
  • The study examined 107 patients using multispiral computed tomography (MSCT) to assess the hard palate's structure, focusing on thickness and width measurements.
  • Results showed considerable variability in hard palate thickness (average 1.74 mm) and width (average 0.9 mm), suggesting these factors are important to consider for successful surgical interventions.
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Exogenous foreign bodies enter the nasal cavity through the nostrils or in some cases through the choana and usually get stuck in the lower or middle nasal meatus. An alien body that has been in the nasal cavity for a long time serves as a nucleus around which calcium and magnesium salts, organic components, are deposited from the nasal secretions, and contributes to the formation of rhinolith (nasal stone, from Greek rhino - nose, lithos - stone). Endogenous material (thick mucous secret or a blood clot drying into the crusts, desquamated epithelium, an atypically located tooth, products of cellular lysis and necrosis of the mucous membrane) can also serve as a potential nucleus for salt deposition.

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The relevance of the problem of chronic inflammatory diseases of the pharynx is due to the significant prevalence of this pathology. Among all forms of chronic pharyngitis, the most adverse effect on the quality of life is observed in chronic athrophic pharyngitis. According to the literature, in this category of patients there are no clear criteria for assessing the functional state and morphological picture of the mucous membrane of the posterior pharyngeal wall.

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Unlabelled: The problem of chronic tonsillitis remains one of the urgent problems of modern otorhinolaryngology. The article discusses the statistics and complications of chronic tonsillitis, provides indications for tonsillectomy and its main complications.

Objective: Generalization and systematization of data on the impact of surgical treatment on the quality of life of patients with chronic tonsillitis.

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The analysis of publications is carried out and current data concerning the etiology, pathogenesis, diagnosis, and principles of treatment of hereditary hemorrhagic telangiectasia are presented.

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The article is devoted to the study of chronic tonsillitis from the point of view of the clinical and morphological picture of the disease, histological changes in the palatine tonsils in various forms of CT. The authors raise the question of studying the assessment of the effect of conservative therapy on the morpho-functional state of the palatine tonsils. The article focuses on the study and influence of extratonsillary oropharyngeal loci of focal infection, such as periodontopathies, on the course of chronic inflammation of the palatine tonsils.

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Unlabelled: Features of the location of the sphenoid sinus determine the possibility of developing severe intraoperative complications in the surgical treatment of patients with chronic sphenoiditis. Technical difficulties during sphenoidotomy may arise at the initial stage of expansion of the natural anastomosis with its anatomical narrowness and the impossibility of inserting biting forceps.

Purpose Of The Study: To study the clinical efficacy and safety of the proposed original method of dilatation of the sphenoid sinus fistula in the surgical treatment of various forms of chronic sphenoiditis.

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The early-life origins of disease hypothesis has been applied to obesity research and modeled through overnutrition, usually with a high-fat diet (HFD). Since the obesity epidemic coincided with societal change in dietary fat consumption, rather than amount, manipulation of fatty acid (FA) profile is an under-investigated area of study. Additionally, the binding of FAs to nuclear receptors may have persistent intergenerational, extranutritive endocrinological effects that interact with the actions of reproductive steroids causing sex-dependent effects.

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Neural imaging benefits from optical access to widespread brain areas. A recent study (Ghanbari et al. Nat.

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