[The role of dysfunction of the autonomic nervous system in idiopathic overactive urinary bladder in women].

A complex urological and neurological examination of female patients with idiopathic overactive bladder (IOAB) has detected clinical signs and neurophysiological correlates of vegetative dysfunction in the form of disturbed sympatho-parasympathic interrelations, failure of segmental and compensatory enhancement of suprasegmental mechanisms of regulation of lower urinary tract activity. The treatment with selective inhibitors of serotonin re-entry reduced severity ofpsychovegetative syndrome and symptoms of the lower urinary tract. This confirms an essential role of the autonomic nervous system in pathogenetic mechanisms of IOAB development and gives grounds for recommending selective inhibitors of serotonin re-entry for combined treatment of IOAB patients.

[Hand motor dysfunctions in computer users].

It were studied 239 female typists aged from 16 to 62 years (mean age 20,1±7,8 years) using author's questionnaire for computer typists to assess hand function and develop preventive measures of disturbances revealed. Indirect signs of tunnel hand neuropathy (27,2%), focal hand dystonia (21,4%) and muscular-tonic syndromes of different localization (18%) have been found. Typists are a risk group of fine hand motor dysfunctions.

[Autonomic imbalance in patients with metabolic syndrome: role in the development of hyperfiltration--an early marker of renal lesions].

Aim: to study the impact of the autonomic nervous system on the development of renal lesion in patients with metabolic syndrome (MS).

Subjects And Methods: One hundred and nine patients (45 females and 54 males) aged 29 to 72 years who had MS were examined. Glomerular filtration rate (GFR) was estimated using the Cockroft-Gault formula, by correcting the obtained result on the body surface.

[Clinical manifestations of migraine in children].

100 case records of children aged 2.5 to 15 years with main complaints of headache (HA) examined and treated in Children's Neurologic Department were analyzed. For making the diagnosis more precise, diagnostic criteria of International Society for HA Investigation (1988) were used.

[Headache syndrome in children with autonomic dysfunction].

Morbidity analysis of 350 children from somatic hospital has revealed clinical manifestations of autonomic dystonia syndrome (ADS) in 36% of the cases in the form of gastrointestinal, cardiovascular disorders, headache syndrome, etc. It was found that in the patients with a prevalence of vagotonia clinical manifestations of ADS rose at earlier age and differed by more variety than in combined and sympathotonic types of autonomic homeostasis. Headache syndrome was rather frequent in ADS and was observed in 35% of the patients.

[The role of clinical-electrophysiological indices in therapy for late-stage residual stroke by dynamic correction of proprioception].

The new method dynamic proprioceptive correction using a medical loading costume was included into complex therapy in patients with late-stage residual stroke. Application of the costume promoted normalization of complex locomotor acts of walking by correcting proprioceptive pulsation resulted from the system of elastic draughts. Thus, a new motor stereotype was forced upon the patients.

[Dynamic proprioceptive correction in the rehabilitation of patients with a late residual stage of stroke].

Space gravity suit has been used for over 20 years in Russian space stations to prevent harmful consequences of being in zero gravity (osteoporosis, muscle atrophies, etc.). The space suit is designed in such a way that it enables to create a payload on muscles, temporarily out of function, which is adequate to the natural one.

New approaches to the rehabilitation of patients with neurological movement defects.

Results were obtained using a new method, based on the "Adeli-92" therapeutic space suit, for the rehabilitation of patients with movement disorders due to acute lesions of the cerebral circulation, head trauma, and other causes. A variety of methods was used to assess the state of patients before and after treatment, including clinical studies, psychological tests, EEG recordings, evoked potential studies, stabilography, and heart rhythm analysis. The results obtained demonstrate the high efficacy of this new method.

[New approaches to the rehabilitation of patients with neurological motor defects].

The results of the application of medical space suit "Adelie-92" for rehabilitation of patients with motor disorders are presented. Brain circulation acute disturbances as well as craniocerebral traumas were the main causes of these motor disorders. The complex estimation of patients condition was carried out both before and after the treatment.

[The epidemiology of autonomic disorders in Moscow schoolchildren].

Epidemiological survey of 2076 schoolchildren in the city of Moscow aged 7-15 revealed vegetative disorders in 63.8% of the examinees. Sex- and age-specific features of clinical presentation, complaints are described.

[Psycho-autonomic correlations in neurocirculatory asthenia in young age].

As many as 91 patients aged 17-25 years seen at the students' outpatient hospital for autonomic disorders, namely for vegetovascular dystonia (VVD) were examined. The data of somatovegetative and psychiatric examinations were compared. It has been shown that the symptomatic diagnosis of VVD may mask both vegetative lability common to the mentally normal and practically healthy subjects and vegetative dystonia syndrome proper, which is a component of psychovegetative syndromes.

[Clinico-physiological characteristics of syncopal conditions in the long QT syndrome (Romano-Ward syndrome)].

A complex of methods including clinical analysis, ECG, and exercise EEG was used to examine 52 patients aged 2 to 20 years with Romano-Ward syndrome. There were two groups: group I with syncopal attacks, group II without them. The patients with Romano-Ward syndrome had dysfunction of the suprasegmental systems regulated autonomously in the form of functional insufficiency of the mesencephalic activating system.

[Chronic nonparoxysmal supraventricular tachycardia in children and adolescents].

An examination was performed in 111 children and adolescents with recurrent and sustained chronic nonparoxysmal tachycardias (CNPT). ECG and electrophysiological studies showed that ante- and retrograde conduction along the accessory atrioventricular junction was the most common mechanisms of arrhythmia. Holter monitoring revealed a high rigidity of cardiac rhythm in patients with sustained CNPT.

[Clinico-psychopathologic and somato-autonomic studies of functional hyperthermia in adolescents].

In a non-psychiatric clinic a combined psychiatric and somato-autonomic investigation was performed in 75 prepuberty and puberty children with functional hyperthermia . Syndromal and nosological characterization was performed on a spectrum of psychic disorders in these patients. Some correlations were found between syndromal and nosological distributions and grouping based on somato-autonomic++ picture.

[Psychoautonomic syndrome in non-infectious subfebrile conditions in children].

To ascertain the cerebral organization and the importance of its specific levels in the occurrence of the thermopathological syndrome associated with vegetovascular dystonia, 40 children aged 8-15 years with non-infectious subfebrile conditions of long standing were examined. The children's status was marked by polysystemic shifts common to the neurogenous disorders. Of crucial significance was dysfunction of the structures of the suprasegmental level (the limbic-reticular complex) of vegetative regulation with the involvement of the specialized hypothalamic centers of thermoregulation, with excessive sympathetic influences at the periphery and formation of the psychovegetative syndrome.

[Status of the autonomic nervous system and reflexotherapy in children with vasomotor rhinitis].

Different variants of vegetative nervous system dysfunction were identified during the examination of 86 children with vasomotor rhinitis. Based on the findings of the examination a pathogenetically-based method of acupuncture was proposed for the management of this patients' group. Acupuncture with regard to vegetative dysfunction attenuated the latter's manifestations and corrected associated psychoemotional disorders.

[Status of cerebral structure and hemodynamics in healthy children and those with autonomic-vascular dystonia].

From the standpoint of traditional neurology an attempt has been made to evaluate the function of the cerebral structures in 50 children with vegetovascular dystonia and 30 normal ones. On the basis of the data obtained a working hypothesis is advanced about a special role of the defect in the right cerebral hemisphere in the pathogenetic mechanisms of hypertension in the presence of vegetovascular dystonia.

[Clinico-physiologic analysis of psychogenic tics in children].

The results obtained in a study of 100 patients formed the basis for major differential diagnostic criteria of psychogenic tics in children. Polygraphic examination of the sleep-wakefulness cycle revealed dysfunctions in the nonspecific cerebral systems in the form of hyperfunction of the activating and insufficiency of the inhibitory apparatuses which were expressed in all functional states in the EEG, motor and vegetative spheres. These changes are considered to be pathogenetically important in view of their connection with the most significant clinical characteristics of the disease.