Publications by authors named "Shuzhen Gan"

Background: Social anxiety disorder (SAD) is characterized by abnormal fear to social cues. Although unisensory processing to social stimuli associated with social anxiety (SA) has been well described, how multisensory processing relates to SA is still open to clarification. Using electroencephalography (EEG) measurement, we investigated the neural correlates of multisensory processing and related temporal dynamics in social anxiety disorder (SAD).

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Deficits in cognitive control have been found in depression, but how they contribute to depressive symptoms remains unknown. The present study investigated whether the regulatory efficacy of cognitive control on negative emotion varies with depression level and whether the regulatory efficacy affects depressive symptoms via the mediation of rumination. Fifty participants screened by the Zung Self-Rating Depressive Scale (SDS) with high and low depression levels were selected.

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This study investigates how the working memory (WM) load influenced the efficacy of cognitive reappraisal, a frequently used strategy for emotion regulation. In a dual-task paradigm, the participants were required to perform a high-load or a low-load memory task and simultaneously reappraise aversive pictures with a negative or a neutral meaning. In the low-load condition, we found that the amplitude of emotion-enhanced late positive potential (LPP) was significantly decreased by neutral reappraisal compared to negative reappraisal.

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Streptococcus suis serotype 2 (S. suis 2)-induced sepsis and meningitis are often accompanied by bacteremia. The evasion of polymorphonuclear leukocyte-mediated phagocytic clearance is central to the establishment of bacteremia caused by S.

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Background: Low-level DNA mutations play important roles in cancer prognosis and treatment. However, most existing methods for the detection of low-level DNA mutations are insufficient for clinical applications because of the high background of wild-type DNA.

Design And Method: In this study, a novel assay based on Tm-dependent inhibition of wild type template amplification was developed.

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The current event-related potential study investigated the modulation effects of different emotion regulation strategies on electrocortical responses. When watching negative or neutral pictures, participants were instructed to perform three tasks: cognitive reappraisal, expressive suppression and passive viewing. We found that negative pictures elicited a larger late positive potential (LPP) than neutral pictures.

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Article Synopsis
  • The study aimed to create a version of the suilysin protein that does not cause hemolysis (destruction of red blood cells) while still retaining its immune response capabilities.
  • Researchers mutated the proline residue at position 353 to three different amino acids (alanine, leucine, and valine) and purified these recombinant proteins to test their hemolytic activity.
  • Among the mutants, SLY(P353V) exhibited no hemolytic activity but still demonstrated significant immunogenicity in further tests.
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Streptococcus suis serotype 2 is a Gram-positive bacterium that causes sepsis and meningitis in piglets and humans. The mechanisms of S. suis serotype 2 invasive disease are not well understood.

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Although its role is frequently stressed in acoustic profile for vocal emotion, sound intensity is frequently regarded as a control parameter in neurocognitive studies of vocal emotion, leaving its role and neural underpinnings unclear. To investigate these issues, we asked participants to rate the angry level of neutral and angry prosodies before and after sound intensity modification in Experiment 1, and recorded electroencephalogram (EEG) for mismatching emotional prosodies with and without sound intensity modification and for matching emotional prosodies while participants performed emotional feature or sound intensity congruity judgment in Experiment 2. It was found that sound intensity modification had significant effect on the rating of angry level for angry prosodies, but not for neutral ones.

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