Dihydroartemisinin Promoted Bone Marrow Mesenchymal Stem Cell Homing and Suppressed Inflammation and Oxidative Stress against Prostate Injury in Chronic Bacterial Prostatitis Mice Model.

Although bone marrow mesenchymal stem cells (BMMSCs) are effective in treating chronic bacterial prostatitis (CBP), the homing of BMMSCs seems to require ultrasound induction. Dihydroartemisinin (DHA) is an important derivative of artemisinin (ART) and has been previously reported to alleviate inflammation and autoimmune diseases. But the effect of DHA on chronic prostatitis (CP) is still unclear.

A simple nomogram prediction model to identify relatively young patients with mild cognitive impairment who may progress to Alzheimer's disease.

Aim: Construct a clinical predictive model based on easily accessible clinical features and imaging data to identify patients 65 years of age and younger with mild cognitive impairment(MCI) who may progress to Alzheimer's disease(AD).

Methods: From the ADNI database, patients with MCI who were less than or equal to 65 years of age and who had been followed for 6-60 months were selected.We collected demographic data, neuropsychological test scale scores, and structural magnetic images of these patients.