Integrated Analysis of Oral Microbiome and Metabolome in T2DM Patients With Varying Glycemic Status.

Objective: This study aimed to analyze the subgingival and salivary microbiome and metabolome in diabetic periodontitis patients with varying glycemic levels.

Methods: Forty-two diabetic periodontitis patients were sampled of saliva, gingival crevicular fluid (GCF), and blood, and categorized into three groups based on systemic glycemic status. The microbiome was assessed using full-length 16S rRNA gene sequencing.

[Analysis of clinical characteristics and risk factors in patients with neuropsychiatric systemic lupus erythematosus (NPSLE)].

Objective To analyze clinical characteristics of patients with neuropsychiatric systemic lupus erythematosus (NPSLE) and to explore the risk factors affecting the occurrence of NPSLE. Methods A total of 63 NPSLE patients and 61 non-NPSLE patients were enrolled. The clinical manifestations and laboratory examination data of the two groups were collected, and the disease characteristics of NPSLE were summarized to analyze the risk factors affecting the occurrence of NPSLE by multivariate Logistic regression.

Interleukin-29 and interleukin-28A induce migration of neutrophils in rheumatoid arthritis.

Objectives: Type III Interferons, interleukin (IL)-29 and IL-28A, have been implicated in the inflammatory response of rheumatoid arthritis (RA). Increasing evidence suggests an important role of neutrophils in the pathogenesis of RA. However, the underlying mechanism remains unclear.

Improvement of partial nitrification endogenous denitrification and phosphorus removal system: Balancing competition between phosphorus and glycogen accumulating organisms to enhance nitrogen removal without initiating phosphorus removal deterioration.

The novel partial nitrification endogenous denitrification and phosphorus removal (PNEDPR) process can achieve deep-level nutrient removal from low carbon/nitrogen municipal wastewater without extra carbons. However, its performance is limited by long hydraulic retention time (HRT) and low specific endogenous denitrification rate (r). This study aimed at investigating the effects of two improving strategies on PNEDPR.

Combining partial nitrification and post endogenous denitrification in an EBPR system for deep-level nutrient removal from low carbon/nitrogen (C/N) domestic wastewater.

In this study, partial nitrification and post endogenous denitrification (PED) were combined with enhancing bacterial phosphorus removal (EBPR) in an anaerobic/aerobic/anoxic operated sequencing batch reactor (SBR) for deep-level nutrient removal from low carbon/nitrogen (C/N, chemical oxygen demand (COD)/total nitrogen (TN)) domestic wastewater. At anaerobic stage, abundant organic matters (96.6% of COD consumption) in raw wastewater were stored as poly-hydroxyalkanoates (PHAs) by phosphorus and glycogen accumulating organisms with enhanced activities, which provided sufficient intracellular carbons for subsequent aerobic phosphorus uptake and anoxic PED.