Synopsis of recent research by authors named "Shuyu Mao"
- Shuyu Mao's recent research focuses on the mechanisms of cancer progression and therapeutic interventions, particularly in thyroid and ovarian cancers, by identifying crucial molecular pathways and genetic mutations, including the PI3K/AKT/mTOR signaling pathway and the POLM G312R variant.
- The studies also delve into the role of APE1 in stress granule formation in ovarian cancer, emphasizing its implications in cancer survival and treatment resistance, while exploring potential novel treatment strategies using non-toxic compounds.
- Additional investigations include the significance of metabolic regulation through molecules like Vanin-1 in brown adipose tissue and post-translational modifications of FEN1 that contribute to DNA repair and cell proliferation, reflecting a broader interest in metabolic homeostasis and genome stability.
