Publications by authors named "Shuyou Wang"

Article Synopsis
  • Interstitial fluid is useful for diagnosing diseases and detecting tumor markers, but collecting it from deep tissues is difficult.
  • This study compared three methods—push-pull perfusion, multi-filament nylon thread implantation, and tissue centrifugation—for collecting interstitial fluid from mini-pigs' subcutaneous tissue.
  • Results showed that while the overall ion composition was similar across methods, there were minor differences in ion detection rates and concentrations, suggesting the choice of method should depend on specific ions or collection locations.
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Electroencephalography (EEG) microstate analysis is a neuroimaging analytical method that has received considerable attention in recent years and is widely used for analysing EEG signals. EEG is easily influenced by internal and external factors, which can affect the repeatability and stability of EEG microstate analysis. However, there have been few reports and publicly available datasets on the repeatability of EEG microstate analysis.

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Background: Visually evaluating liver function is a hot topic in hepatology research. There are few reliable and practical visualization methods for evaluating the liver function in experimental studies. In this study, we established a multimodal imaging approach for liver function evaluation and compared healthy mice with chronic alcoholic liver injury (cALI) model mice to explore its potential applicability in experimental research.

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Background: The biophysical properties of the meridian system, an important concept of traditional Chinese medicine, include low impedance, resounding voice, and high acoustic conductance, all of which are helpful for elucidating the essence of meridians.

Objectives: To visualize the human pericardium meridian (PC) based on the resounding voice property of meridians.

Methods: Visualization of the PC was performed by injection of fluorescein sodium at the PC6 acupoint (Neiguan) on the PC.

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Skin blood flux (SkBF) changes caused by drinking cold water are generally associated with vagal tone and osmotic factors in the digestive system. However, there is still a lack of relevant research on whether there are left and right differences in these SkBF change. In the current study, a total of 60 subjects were recruited.

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Objective: Acupuncture can improve the symptoms of alcohol-induced bodily injury and has been accepted by the World Health Organization. In this study, fluorescence imaging (IVFI) was applied to display and evaluate the effect of electroacupuncture (EA) on liver function (LF) in mice with chronic alcoholic liver injury (cALI).

Methods: IVFI of the Cy5.

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High-precision tension control is very important for industrial production. Benefit from the unique property of magnetorheological (MR) fluid, a MR clutch is a potential device in a tension control system due to its fast response and large output dynamics. In this paper, based on the detailed analysis of axial magnetic induction intensity generated by the coil along the radial distribution, a shear-mode MR clutch with uniform magnetic field distribution along the radial direction is proposed for the tension control system.

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The Selective Laser Melting (SLM) technique has attracted attention in a wide range of manufacturing research areas, including the defense industry because of its high efficiency and good consistency of manufactured material properties. Shaped charge liner is the crucial unit in the shaped charge warhead. However, jet performance formed by SLM-produced liner remains to be studied systematically.

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Previous studies have explored the relationship between the complexity of local blood flow signals and heart rate variability (HRV) under different thermal stimulations. However, the relationship between the complexity of local blood flow signals and HRV in different positions is not clear. In this study, healthy participants were placed in different body positions.

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In more than half a century, exploring the biological connotation of the meridians was one of the core components of scientific research studies in traditional Chinese medicine (TCM). Based on the previous works of low hydraulic resistance channel (LHRC) along meridians (LHRCM), the differential proteomics between the Alcian blue track (ABT) on LHRC along the conception vessel (CV) and nonmeridians tissue next to the CV were investigated in this study to explore the material basis and biological function of LHRCM. Proteomics based on LC-MS was introduced into the subcutaneous connective tissues (SCT) of ABT along the CV and the adjacent nonmeridian (1 cm from the CV).

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Objective: To observe the effect of electroacupuncture (EA) on the hemorheology and hepatic microcirculation in mice with chronic alcoholic liver injury (cALI), so as to explore the microcirculation mechanism of EA underlying regulating liver function in cALI mice.

Methods: Forty Kunming mice were randomly assigned to control, model, acupoint EA and non-acupoint EA groups, with 10 mice in each group. The cALI model was established by gavage with 50% ethanol (15 mL/kg,2 times per day with 8 hours' interval) for 28 d.

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Objective: To observe the effect of electroacupuncture (EA) on liver surface blood perfusion and related indexes of oxidative stress in mice with acute alcoholic liver injury (AALI), so as to explore its mechanism underlying improving of AALI.

Methods: Twenty-four Kunming mice were randomly divided into control, model and EA groups (8 mice/group). AALI model was established by intragastric administration of 50% ethanol at 6 g/kg.

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The visual evaluation of liver function (LF) has always been a hot topic in research on liver diseases. In vivo fluorescence imaging (IVFI) of the Cy5.5-galactosylated polylysine (Cy5.

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Scalp acupuncture is a somatic stimulation therapy that produces prominent clinical effects when used to treat cerebral diseases. However, this acupuncture's therapeutic mechanisms have not yet been well-addressed. Scalp acupoints are innervated by the trigeminal nerve, which is coincident with the intracranial sensory afferents as well as with the meningeal vessels.

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Objective: To perform quantitative observation on the color change of local skin after cupping, so as to explore objective and quantitative methods for skin response of cupping.

Methods: Seven health subjects were included. By quantitative meridian cupping instrument, cupping methods with four types of pressures were respectively performed on subjects for 5 min.

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The objective of this study was to investigate the spectra characteristics (SC) at wavelengths of 400~1000 nm and 2.5~15.5 m of pure moxa stick (MS) during its 25-minute burning process using new spectral imaging techniques.

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Imaging methods to evaluate hepatic microcirculation (HM) and liver function (LF) by directly monitoring overall liver tissue remain lacking. This study establish imaging methods for LF that combines Laser speckle perfusion imaging (LSPI) and in vivo optical imaging (IVOI) technologies to investigate changes of hepatic microcirculation and reserve function in the animals gavaged with 50% ethanol (15 ml/kg·bw) for a model of acute alcoholic liver injury (ALI), and for evaluation of electroacupuncture (EA) effect. The liver blood perfusion and indocyanine green (ICG) distribution were observe by LSPI and IVOI separately.

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The study is to observe the influence of electroacupuncture (EA) stimulation at "Zusanli" (ST36) on the release of nitric oxide (NO) and blood perfusion (BP) in the liver and further explore whether the hepatic blood perfusion (HBP) changes were regulated by EA ST36 induced NO in nitric oxide synthase inhibited mice. The HBP change of the mice was detected by laser speckle perfusion imaging (LSPI) before and after being given interventions, and the NO in liver tissue was detected by nitric acid reductase in each group. The NO levels and HBP in the L-NAME group were significantly lower than those in the control group (P < 0.

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This study was to observe the effects of acupuncture and moxibustion on spectrum features of acupoint using hyperspectral imaging (HSI) technique. HSI of the Neiguan (PC6) in the acupuncture groups, moxibustion groups, and control groups was scanned by the hyperspectral imager to analyze the spectrum features and the variations within the wavelength of 400-1000 nm and explore the relationship between the spectral characteristics and effects of acupuncture and moxibustion. The light absorption intensity was slightly reduced within the wave band of 540-590 nm after acupuncture.

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The study was conducted to observe the effect of electroacupuncture (EA) on hepatic blood perfusion (HBP) and vascular regulation. We investigated 60 male anesthetized mice under the following 3 conditions: without EA stimulation (control group); EA stimulation at Zusanli (ST36 group); EA stimulation at nonacupoint (NA group) during 30 min. The HBP was measured using the laser speckle perfusion imaging (LSPI).

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Objective: To observe the influence of electroacupuncture (EA) on indocyanine green (ICG) metabolism in the liver and the action mechanism of acupuncture for hepatic regulation.

Methods: Forty Kunming mice were randomly divided into an EA group and a control group, 20 cases in each one. Combined with classical hepatic metabolism test of ICG, after tail vein injection of ICG, twenty mice were treated with EA at "Zusanli" (ST 36) for 20 min.

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Objective: To observe the blood perfusion levels in different facial acupoint regions and changes after acupuncture stimulation of Hegu (LI 4).

Methods: Thirty healthy volunteer subjects were equally divided into control group and acupuncture group. Blood perfusion levels of different facial acupoint areas were detected using a Laser Doppler Imager.

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Objective: To observe the effect of electroacupuncture (EA) of "Taichong" (LR 3) on liver function in rats with mild alcoholic liver injury (MALI) so as to explore the feasibility of acupuncture in improving mild alcoholic liver injury.

Methods: Forty SD rats were randomly divided into control, model, EA-LR 3 and EA-non-acupoint groups (10 rats/group). MALI model was duplicated by intragastric administration of distillate spirit (14 mL/kg) for 12 hours.

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Objective: To investigate the relationship between the temperature and the microvascular blood flow of the cerebral cortex, and the influence of electro-acupuncture (EA) on the cortical microcirculation.

Methods: High temperature spots on the anterior ectosylvian and low temperature spots on the posterior suprasylvian on the cortical surface of 20 cats were identified using cortical infrared thermography (CIT); the blood flow in the microcirculation on these spots was measured with laser-Doppler flowmetry. EA was given at Zusanli (ST 36) and changes in the blood flow in the cerebral cortex microcirculation were detected.

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Objective: To observe the content of leptin in the abdominal subcutaneous tissues of the higher temperature zone along the Gallbladder (GB) Meridian in cholecystitis rabbits so as to explore the correlation between the temperature response and the leptin level.

Methods: Twenty-five rabbits were randomized into normal control group (n = 10) and cholecystitis model group (n = 15). Cholecystitis model was established by injection of Escherichia coli solution (0.

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