Molecularly imprinted FeO nanoparticles-based magnetic 3D photonic crystal microspheres for specific adsorption of aflatoxin B in grains.

Aflatoxin B (AFB) is the major toxic mycotoxin that contaminates grains at trace levels, necessitating the development of an efficient and simple extraction method to enrich it in samples. Here, magnetic molecularly imprinted FeO nanoparticles (MMIPs) were first synthesized by employing 5,7-dimethoxy coumarin as the template and methacrylic acid combined with styrene as the functional monomers. These MMIPs exhibited excellent selective recognition capabilities for AFB, based on which, a novel molecularly imprinted magnetic inverse opal photonic crystal microsphere (MIP@MIPCM) was fabricated via a droplet-based microfluidic self-assembly technique.