Exosomes are a class of extracellular vesicles that encompass a diverse array of bioactive molecules, including proteins, lipids, mRNA, and microRNA(miRNA). Virtually all cell types release exosomes under both physiological and pathological conditions. In addition to electrical and chemical signals, exosomes are an alternative route of signaling between cells in the brain.
View Article and Find Full Text PDFExposure to fine particulate matter (PM2.5) is associated with increased morbidity and mortality among patients with idiopathic pulmonary fibrosis (IPF). Pathological alterations in IPF typically originate in the subpleural regions of the lungs.
View Article and Find Full Text PDFBackground: Interleukin-10 (IL-10), a pivotal anti-inflammatory cytokine, has gotten attention for its involvement in tissue remodeling and organ fibrosis. Pleurisy and subsequent pleural remodeling are recognized as quantifiable indicators of systemic lupus erythematosus (SLE) activity. However, the role of IL-10 in SLE-associated pleural remodeling remains unknown.
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November 2024
Human tissue-resident memory T (T) cells play a crucial role in protecting the body from infections and cancers. Recent research observed increased numbers of T cells in the lung tissues of idiopathic pulmonary fibrosis patients. However, the functional consequences of T cells in pulmonary fibrosis remain unclear.
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