Helenine blocks NLRP3 activation by disrupting the NEK7-NLRP3 interaction and ameliorates inflammatory diseases.

Background: The involvement of NLRP3 inflammasome is associated with the progress of numerous inflammatory conditions. However, there is currently no single compound used in the clinic. Search for the inhibitor of NLRP3 inflammasome from natural products is an attractive direction.

Coupling of nitrifying granular sludge into microbial fuel cell system for wastewater treatment: System performance, electricity production and microbial community shift.

A novel electrochemical system coupling of nitrifying granular sludge (NGS) into microbial fuel cell (MFC) system was conducted for simultaneous electricity production and wastewater treatment under sequencing batch mode. After 60 days operation, the contaminants of organic and NH-N removal efficiencies of the system were high of 95.43% and 98.