Vertical migration characteristics of polychlorinated biphenyls (PCBs) in estuarine and coastal zones under complex environmental conditions.

As a transitional zone where rivers meet the sea, estuaries are influenced by river transport and ocean tides, resulting in complex variations in parameters such as organic matter content, pH, and sediment salinity. This paper primarily explores the vertical migration patterns of polychlorinated biphenyls (PCBs) under complex conditions, focusing on the soil sediments in the Dagu River estuary area. We designed an indoor soil column leaching experiment to investigate how soil organic matter content, pH, and salinity affect the vertical migration of PCBs in soil.

Effects of iodine content on the hydrochemical characteristics and microbial community structure of groundwater in coastal zone: A case study of Bailang River Basin.

Iodine is an important component of the thyroid gland, producing hormones. Excess iodine can trigger autoimmune thyroid disease. The salt-freshwater interaction zone of the coastal aquifer is affected by seawater intrusion, and the physical and chemical environment is constantly changing.

Significant changes in the physicochemical properties of BC-containing particles during the cold season in Beijing.

The ambient air quality has improved significantly under strict emission controls in Beijing, China over the last decade. Black carbon (BC), as a short-lived climate forcer in ambient aerosols, profoundly impacts the air quality and climate. Previous studies have demonstrated a decline in the mass concentration of BC.

Dynamic characteristics and evolution laws of underground brine in Mahai salt lake of Qaidam Basin during mining process.

In the late stage of underground brine mining in salt lakes, the method of injecting fresh water is often used to extract the salt from the brine storage medium. This method of freshwater displacement breaks the original water-rock equilibrium and changes the evolution process of the original underground brine. To explore the mechanism of salt release in saline water-bearing media under conditions of relatively fresh lake water dissolution, this paper analyzes the changes in the chemical parameters of brine from 168 sampling points in the Mahai salt lake in the Qaidam Basin at three stages (before exploitation, during exploitation, and late exploitation) by correlation analysis, ion ratio analysis, and other methods and investigate the variations in porosity and the evolution laws of brine.

Assessment of heavy metal accumulation and potential risks in surface sediment of estuary area: A case study of Dagu river.

Soil/sediment samples of four different land types were collected from aquaculture land, farmland, industrial land and river bottom sediment in the estuary area of Dagu River. The contents of Cr, Cu, Zn, As, Cd and Pb in 0-30 cm inner surface samples were detected, and the distribution characteristics of heavy metal content in surface soil/sediment of different land use types in the estuary area were analyzed. Local accumulation index method, potential risk index evaluation method and principal component analysis method were used to analyze the pollution status and sources of heavy metals.

Resolving Ultraviolet-Visible Spectra for Complex Dissolved Mixtures of Multitudinous Organic Matters in Aerosols.

Light-absorbing organic aerosols, referred to as brown carbon (BrC), play a vital role in the global climate and air quality. Due to the complexity of BrC chromophores, the identified absorbing substances in the ambient atmosphere are very limited. However, without comprehensive knowledge of the complex absorbing compounds in BrC, our understanding of its sources, formation, and evolution mechanisms remains superficial, leading to great uncertainty in climatic and atmospheric models.

Distribution, sources, and ecological risk assessment of polychlorinated biphenyls (PCBs) in the estuary of Dagu River, China.

Four different types of 0-30 cm soil/sediment samples were collected from aquaculture land, farmland, industrial land and river bottom sediment in the estuary area of Dagu River, and the pollution status and sources of 7 PCB congeners were analyzed. The results showed that the mean values of ΣPCBs in soil/sediments of different land use types were 5.01 ng g dw for industrial land, 3.

Hyalinising clear cell carcinoma of the lung: A case report and review of literature.

Background: Hyalinising clear cell carcinoma (HCCC) of the lung is a rare tumor, with only 12 reported cases. To improve the differential diagnosis, the aim of this study was to clarify the clinicopathological characteristics, immunophenotype, and molecular characteristics of HCCC of the lung and relate these to prognosis.

Methods: Sections of HCCC of the lung were collected from a patient for pathological observation, immunohistochemistry, histochemistry, and fluorescence in situ hybridization; the clinical, pathological, and molecular characteristics were compared with those reported in the literature.

Does environmental uncertainty of enterprises aggravate the accrual anomaly in the stock market? Evidence from China.

Enterprises do not exist independently of the external environment, so uncertainty affects their earnings volatility and exacerbates the information asymmetry between internal and external stakeholders. As a major manifestation of capital market mispricing, the accrual anomaly is caused by investors' functional fixation on total surplus under information asymmetry. Against this backdrop, taking A-share listed companies in China from 2007 to 2019 as our research objects, this study explores the impact of environmental uncertainty on the accrual anomaly based on the information asymmetry and investor irrationality perspective.

Secondary organic aerosol formation in China from urban-lifestyle sources: Vehicle exhaust and cooking emission.

An increasing number of people tend to live in cities, where they suffer from serious air pollution from anthropogenic sources. Vehicle exhaust and cooking emission are closely related to daily life of urban residents, and could be defined as "urban-lifestyle sources". The primary emissions of urban-lifestyle sources tend to form abundant secondary organic aerosols (SOA) through complicated atmospheric chemistry processes.

Aqueous secondary organic aerosol formation attributed to phenols from biomass burning.

Biomass burning emits large quantities of phenols, which readily partition into the atmospheric aqueous phase and subsequently may react to produce aqueous secondary organic aerosol (aqSOA). For the first time, we quantitatively explored the influence of phenols emitted from biomass burning on aqSOA formation in the winter of Beijing. A typical haze episode associated with significant aqSOA formation was captured.

A preliminary study on the eco-environmental geological issue of in-situ oil shale mining by a physical model.

As traditional methods of oil shale production emitting high levels of pollutants, in-situ exploitation has aroused great concerns. In order to study the effect of in-situ pyrolysis products on the underground environment, an in-situ oil shale exploitation of underground environment impact laboratory simulation system was designed. Based on the hydrogeological condition of oil shale area in Nong'an City, a physical simulation test was conducted.

Current challenges of improving visibility due to increasing nitrate fraction in PM during the haze days in Beijing, China.

The annual mean PM mass concentration has decreased because of the stringent emission controls implemented in Beijing, China in recent years, whereas the nitrate NO mass fraction in PM increases gradually. Low-visibility events occur frequently even though PM pollution has been mitigated significantly, with the daily mean PM mass concentration mostly less than 75 μg/m. In this study, the non-linear relationship was analyzed between atmospheric visibility and PM based on chemical composition from a two-year field observation.

The effect of hepatocellular carcinoma-associated fibroblasts on hepatoma vasculogenic mimicry.

Vasculogenic Mimicry (VM) is the main source of blood supply in the early stage of tumor growth. Carcinoma-associated fibroblasts (CAFs) are one of the most important host cells in the tumor microenvironment. Some studies have found that CAFs can promote tumor angiogenesis, but there are few reports on the relationship between CAFs and VM.

[Responses of soil potential carbon/nitrogen mineralization and microbial activities to extreme droughts in a meadow steppe].

The mineralization of soil carbon (C) and nitrogen (N) is a critical process in the cycling of C and N in terrestrial ecosystems, which is strongly controlled by water availability. In this study, we collected soil samples in a 3-year extreme drought experiment in a meadow steppe in Inner Mongolia, freeze-dried these samples, and measured the potential C and N mineralization rates and water sensitivity of soil microorganism by incubating soils under soil water contents (SWC) of 3%, 8%, 13%, 18%, 25% and 35%. The results showed that averaged across different SWC, the extreme drought treatment of reducing 66% precipitation in growing season significantly increased potential N mineralization rate by 14.

The influence of oil shale in situ mining on groundwater environment: A water-rock interaction study.

Oil shale samples were obtained from Nong'an oil shale ore-bearing area which was located in the southeastern uplift of Songliao basin, China. The XRD test for oil shale identified the minerals in it and a series of water-rock interaction experiment between oil shale-water and oil shale ash-water were carried out to the study the release of organic matter from groundwater during oil shale in-situ exploitation. The content of phenol, BTEX, TOC and TPH in oil shale and oil shale ash aqueous solution were determined.

Levels and distribution of synthetic musks in farmland soils from the Three Northeast Provinces of China.

The levels and distribution of synthetic musks (ADBI, AHMI, ATII, HHCB, AHTN, MX and MK) were investigated in farmland soils from the Three Northeast Provinces of China. The total concentrations of SMs ranged from 2.40 ng/g to 12.

DHS (trans-4,4'-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2).

DNA replication machinery is responsible for accurate and efficient duplication of the chromosome. Since inhibition of DNA replication can lead to replication fork stalling, resulting in DNA damage and apoptotic death, inhibitors of DNA replication are commonly used in cancer chemotherapy. Ribonucleotide reductase (RNR) is the rate-limiting enzyme in the biosynthesis of deoxyribonucleoside triphosphates (dNTPs) that are essential for DNA replication and DNA damage repair.

Differences in silencing of mismatched targets by sliced versus diced siRNAs.

It has been reported that the two major types of RNA interference triggers, the classical Dicer-generated small RNAs (siRNAs), which function with all members of the Argonaute (Ago) protein family in mammals, and the Ago2-sliced small RNAs (sli-siRNAs), which function solely through Ago2, have similar potency in target cleavage and repression. Here, we show that sli-siRNAs are generally more potent than siRNAs in silencing mismatched targets. This phenomenon is usually more apparent in targets that have mismatched nucleotides in the 3' supplementary region than in targets with mismatches in the seed region.

Enhanced removal of bisphenol-AF by activated carbon-alginate beads with cetyltrimethyl ammonium bromide.

Adsorption removal of bisphenol-AF (BPAF) from aqueous solutions by synthesized activated carbon-alginate beads (AC-AB) with cetyltrimethyl ammonium bromide (CTAB) has been studied using two ways. The traditional method (two-step) first synthesized CTAB-modified AC-AB (AC-AB-CTAB), then used it to remove BPAF by adsorption. And one-step method dispersed AC-AB and CTAB in wastewater, followed by the removal of BPAF accompanied with the synthesis of AC-AB-CTAB.

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress.

Ribonucleotide reductase small subunit B (RRM2B) is a stress response protein that protects normal human fibroblasts from oxidative stress. However, the underlying mechanism that governs this function is not entirely understood. To identify factors that interact with RRM2B and mediate anti-oxidation function, large-scale purification of human Flag-tagged RRM2B complexes was performed.

Autophagy induction causes a synthetic lethal sensitization to ribonucleotide reductase inhibition in breast cancer cells.

Macroautophagy can promote cellular survival or death depending on the cellular context and its extent. We hypothesized that autophagy induction would synergize with a therapeutic agent targeting the autophagic cargo. To test this hypothesis, we treated breast cancer MDA-MB-231 cells with tamoxifen (TMX), which induces autophagy through an estrogen receptor-independent pathway.