Circ_0070203 Promotes Epithelial-mesenchymal Transition in Ovarian Serous Cystadenocarcinoma through miR-370-3p/TGFβR2 Axis.

Introduction: Circular RNAs (circRNAs) are important biological molecules associated with the pathogenesis of multiple cancers.

Objective: This work aimed to investigate the function and molecular mechanism of circ_0070203 in high-grade serous ovarian cystadenocarcinoma (HGSOC).

Methods: circRNA microarray was conducted to detect the circ_0070203 expression in HGSOC tissues.

A study of adverse maternal-foetal outcomes in nephrotic syndrome combined with preeclampsia.

Background: Although the majority of pregnancies with preeclampsia are characterised by elevated blood pressure, preeclampsia is often associated with nephrotic syndrome with similar symptoms such as high proteinuria and bilateral lower limb oedema. In this study, we compared the maternal-foetal outcomes of pregnant women with preeclampsia in a population with nephrotic syndrome and explored the factors that contribute to the corresponding outcomes and disease development.

Methods: A total of 90 pregnant women were included in this study, of whom 30 had nephrotic syndrome and were diagnosed with preeclampsia during pregnancy, and 60 had nephrotic syndrome alone.

Evaluation of frailty status among older people living in urban communities by Edmonton Frail Scale in Wuhu, China: a cross-sectional study.

Background: Few studies have explored the factors that are associated with frailty among older people.

Objective: To investigate the frailty status and examine the sociodemographic factors that are associated with of older peoples' frailty status in China.

Design: Cross-sectional study.

Clinical significance of KAI1/CD82 protein expression in nasopharyngeal carcinoma.

The aim of this study was to investigate KAI1/CD82 protein expression in human nasopharyngeal carcinoma (NPC) cell lines and human NPC tissues. Immunohistochemistry and western blot analysis were used to detect the localization and expression levels of the KAI1/CD82 protein in five human NPC cell lines. Immunohistochemistry was also conducted to detect the expression of the KAI1/CD82 protein in 70 NPC tissues and 30 non-neoplastic nasopharyngeal tissues.

[The application of epiglottis and cervical anterior muscle to laryngeal reconstruction].

Objective: To evaluate the methods of reconstruction of laryngeal function after the extended laryngectomy.

Methods: The laryngeal functions were reconstructed after the extended laryngectomy performed on 22 cases with the laryngocarcinoma of T2 and T3 stages of glottic type, using epiglottis and cervical anterior muscle to reconstruct the laryngeal cavity and larynx bracket, from September 1998 to October 1999.

Results: Twenty cases recovered normal swallow function in 20 days post-operation as well as the entire function of larynx was recovered, and the rate of decannulation was 90.