Pharmacodynamic components and molecular mechanism of Gastrodia elata Blume in treating hypertension: absorbed components, network pharmacology analysis, molecular docking and in vivo experimental verification.

Ethnopharmacological Relevance: Rhizome of Gastrodia elata Blume (RGE) is a valuable traditional Chinese Medicine (TCM) in the clinical practice. The Compendium of Materia Medica records that RGE has the effect of flatting liver wind out. It has sedative, analgesic, hypnotic, anticonvulsant, anti-hypertensive, anti-myocardial ischemia, anti-arrhythmic and anti-platelet aggregation effects.

To explore the effect of kaempferol on non-small cell lung cancer based on network pharmacology and molecular docking.

Non-small cell lung cancer (NSCLC) is a common pathological type of lung cancer, which has a serious impact on human life, health, psychology and life. At present, chemotherapy, targeted therapy and other methods commonly used in clinic are prone to drug resistance and toxic side effects. Natural extracts of traditional Chinese medicine (TCM) have attracted wide attention in cancer treatment because of their small toxic and side effects.

On the preconditioned GAOR method for a linear complementarity problem with an -matrix.

Recently, based on the Hadjidimos preconditioner, a preconditioned GAOR method was proposed for solving the linear complementarity problem (Liu and Li in East Asian J. Appl. Math.