METS-IR/HOMA-IR and MAFLD in U.S. adults: dose-response correlation and the effect mediated by physical activity.

Objectives: Metabolic dysfunction-associated fatty liver disease (MAFLD), a globally prevalent disease, is closely linked to insulin resistance (IR). Physical activity (PA) is closely linked to both MAFLD and IR. We aim to explore the dose-response relationship between metabolic score for IR (METS-IR)/homeostasis model assessment of IR (HOMA-IR) and MAFLD, and investigate the relationship between PA, IR and MAFLD.

Effective Degradation of Brewer Spent Grains by a Novel Thermostable GH10 Xylanase.

Brewer spent grains (BSGs) are one of the most abundant by-products in brewing industry. Due to microbiological instability and high perishability, the efficient degradation of BSGs is of environmental and economic importance. Streptomyces sp.

Investigating the effect of exercise on the expression of genes related to cardiac physiological hypertrophy.

Physiological hypertrophy of the heart is associated with an increase in the normal function of the heart, and it directly relates to regular exercise, especially among elite athletes. Researches about special signaling pathways that create physiological hypertrophy have recently received more attention. As a result, the present study was conducted to investigate the effect of aerobic exercise intensity on the expression of genes involved in heart physiological hypertrophy.

Prediction of MAFLD and NAFLD using different screening indexes: A cross-sectional study in U.S. adults.

Introduction: Metabolic dysfunction-associated fatty liver disease (MAFLD), formerly known as non-alcoholic fatty liver disease (NAFLD), has become the most common chronic liver disease worldwide. We aimed to explore the gender-related association between nine indexes (BMI/WC/VAI/LAP/WHtR/TyG/TyG-BMI/TyG-WC/TyG-WHtR) and MAFLD/NAFLD and examine their diagnostic utility for these conditions.

Methods: Eligible participants were screened from the 2017-2018 cycle data of National Health and Nutrition Examination Survey (NHANES).

A thermostable and CBM2-linked GH10 xylanase from for paper bleaching.

Xylanases have the potential to be used as bio-deinking and bio-bleaching materials and their application will decrease the consumption of the chlorine-based chemicals currently used for this purpose. However, xylanases with specific properties could act effectively, such as having significant thermostability and alkali resistance, etc. In this study, we found that Xyl10A, a xylanase from , was greatly induced to transcript by microcrystalline cellulose (MCC) substrate.

Functional Specificity of Three α-Arabinofuranosidases from Different Glycoside Hydrolase Families in An76.

α-l-Arabinofuranosidase (Abf), a debranching enzyme that can remove arabinose substituents from arabinoxylan, promotes the hydrolysis of hemicellulose in plant biomass. However, the functional specificity of Abfs from different glycoside hydrolase (GH) families on the digestion of arabinoxylan and their synergistic interaction with xylanase have not been systematically studied. In this work, we characterized three Abfs (AxhA, AbfB, and AbfC) from GH62, GH54, and GH51 families in An76.

Amplitude-integrated electroencephalography improves the predictive ability of acute bilirubin encephalopathy.

Background: To establish a clinical prediction model of acute bilirubin encephalopathy (ABE) using amplitude-integrated electroencephalography (aEEG).

Methods: A total of 114 neonatal hyperbilirubinemia patients in the Beijing Chaoyang Hospital from August 2015 to October 2018 were enrolled in this study. There were 62 (54.

Attentional bias of subliminal emotional faces in adolescents with obsessive-compulsive disorder.

Attentional bias to threatening information may play a vital role in the onset and maintenance of obsessive-compulsive disorder (OCD). This study aimed to explore whether adolescents with OCD exhibited attentional bias toward faces that express disgust or fear. Participants were 27 adolescents with a first-time primary diagnosis of OCD and 27 healthy controls.

Biophysical signal transduction in cancer cells: Understanding its role in cancer pathogenesis and treatment.

Signaling between cells can promote both the development and progression of cancer. It has been found that chemical and physical signals, together with extracellular factors, can influence cancer progression. In this review, we focus on the physical microenvironment of cancer cells and examine the action of mechanical, electromagnetic, thermal, and acoustic signals on cancer cells, which may provide new directions for cancer research and treatment.

Blind Estimation of the PN Sequence of A DSSS Signal Using A Modified Online Unsupervised Learning Machine.

Direct sequence spread spectrum (DSSS) signals are now widely used in air and underwater acoustic communications. A receiver which does not know the pseudo-random (PN) sequence cannot demodulate the DSSS signal. In this paper, firstly, the principle of principal component analysis (PCA) for PN sequence estimation of the DSSS signal is analyzed, then a modified online unsupervised learning machine (LEAP) is introduced for PCA.

An Improved Velocity Estimation Method for Wideband Multi-Highlight Target Echoes in Active Sonar Systems.

In active sonar systems, the target echoes are usually equivalent to a superposition of the Doppler-scaled reflections from multiple highlights. The reflections overlap with each other both in the time and frequency domain, which results in a decreased velocity estimation performance. Recently, the hyperbolic-frequency modulated signal has been widely employed in sonar systems for moving targets due to its Doppler tolerance, while the precise velocity estimation becomes a great challenge under such conditions.

Effect of Hydraulic Retention Time on Anaerobic Digestion of Wheat Straw in the Semicontinuous Continuous Stirred-Tank Reactors.

Three semicontinuous continuous stirred-tank reactors (CSTR) operating at mesophilic conditions (35°C) were used to investigate the effect of hydraulic retention time (HRT) on anaerobic digestion of wheat straw. The results showed that the average biogas production with HRT of 20, 40, and 60 days was 46.8, 79.

Immobilization of proline-specific endoprotease on nonporous silica nanoparticles functionalized with amino group.

Enzyme immobilization is believed to provide an excellent base for increasing environmental tolerance of enzyme and considerable period of time. In this work, a kind of nonporous silica nanoparticles functionalized with amino group was synthesized to immobilize proline-specific endoprotease (PSEP). PSEP is known to specifically cleave peptides (or esters) at the carboxyl side of proline, thus can prevent the formation of haze and prolong the shelf life of beer.

Prevention of toxigenic fungal growth in stored grains by carbon dioxide detection.

The growth of toxigenic fungi can adversely affect grain quality and even produce mycotoxins of food safety concern, which should be sensitively monitored and controlled during grain storage. To establish the relationship between the growth of toxigenic fungi and their carbon dioxide (CO2) production, the pattern of CO2 concentration changes was studied during the fungal growth in grain. The results showed the CO2 concentrations increased exponentially (r ≥ 0.