Stable Microporous Metal-Organic Framework Based on Tritopic Pyrazolate Ligand for Xe/Kr Separation.

Pyrazolate ligands, renowned for their potent electron-donating capabilities, have emerged as promising building blocks for the construction of stable metal-organic frameworks (MOFs) particularly when paired with late transition metals. While a plethora of diverse MOFs have been meticulously crafted using ditopic pyrazolate ligands, the realm of multidentate pyrazolate-based MOF structures remains relatively unexplored. This research unveils a notable achievement in the synthesis of a novel three-dimensional microporous MOF, characterized by its single-crystal form, meticulously assembled from a tritopic pyrazole ligand and cobalt ions.

One ligand, two roles: novel pillar-layered metal-organic frameworks built with a 3D ligand and asymmetric inorganic nodes.

Herein, we show two cases of pillar-layered MOFs which are built solely with one kind of three-dimensional (3D) ditopic ligand. The ligand in both structures functions not only as an intralayer linker in the layer but also as a "pillar" between adjacent layers. Such multi-functionality of the linker is accompanied by uncommon asymmetric 10- metal hexamer or 7- tetramer nodes, which have never been reported in previous 3D MOF structures.

The mitochondria-targeted antioxidant MitoQ ameliorates inorganic arsenic-induced DCs/Th1/Th2/Th17/Treg differentiation partially by activating PINK1-mediated mitophagy in murine liver.

Inorganic arsenic is a well-established environmental toxicant linked to acute liver injury, fibrosis, and cancer. While oxidative stress, pyroptosis, and ferroptosis are known contributors, the role of PTEN-induced kinase 1 (PINK1)-mediated mitophagy in arsenic-induced hepatic immunotoxicity remains underexplored. Our study revealed that acute arsenic exposure prompts differentiation of hepatic dendritic cells (DCs) and T helper (Th) 1, Th2, Th17, and regulatory T (Treg) cells, alongside increased transcription factors and cytokines.

Soluble urokinase plasminogen activator receptor is associated with cardiovascular calcification in peritoneal dialysis patients.

Background: Cardiovascular disease (CVD) is an important cause of morbidity and mortality in peritoneal dialysis (PD) patients. Cardiovascular calcification (CVC) is highly prevalent in PD patients and could predict their cardiovascular mortality. Soluble urokinase plasminogen activator receptor (suPAR) is closely associated with coronary artery calcification in hemodialysis patients and is an important predictor of CVD.

Cardiac valve calcification as a predictor of cardiovascular outcomes in peritoneal dialysis patients: an inverse probability of treatment weighting analysis.

Background: Cardiovascular events (CVE) are the leading cause of death in peritoneal dialysis (PD) patients. The predictive value of cardiac valve calcification (CVC) for CVE in dialysis patients remains controversial. In particular, such studies are limited in PD patients.

AIE-active aurones for circularly polarized luminescence and trace water detection.

AIE-active phenyl- and [2.2]paracyclophanyl-based aurones (2-Ph and 2-PCP) were synthesized and investigated with different structures and photophysical properties. The results illustrated that the PCP ring can provide chirality, electron-donating ability and steric hindrance.

New crystalline 1D/2D/3D indium selenides directed by piperidine and auxiliary solvents.

The construction of cluster-based crystalline chalcogenide structures through the traditional solvothermal method relies on synergistic control of precursors, template cations and auxiliary solvents. Generally, the combination of metal precursors plays a crucial role in controlling the size of clusters, while organic templates and auxiliary solvents usually contribute to the type of clusters and architecture of the framework. Decades of synthetic efforts have been mainly devoted to expanding organic amine templates for constructing new structures.

3D Boranil Complexes with Aggregation-Amplified Circularly Polarized Luminescence.

The development of small organic CPL-active molecules with large luminescent dissymmetry factors is highly demanded due to their promising applications in chiroptical devices and sensors. This work describes the design and synthesis of a new family of CPL-active BF complexes, ()/()--, which were constructed by fusing a N̂O-chelated BF complex with [2.2]paracyclophane.

Planar chiral [2.2]paracyclophanyl-based boron fluoride complexes: synthesis, crystal structure and photophysical properties.

Planar chiral [2.2]paracyclophanyl-based boron fluoride complexes (3a-3d) were designed and facilely synthesized. The X-ray structure study, theoretical calculations and CD spectra reveal the intense emission and planar chiral structures of these complexes.

Bonded- and discreted-Lindqvist hexatungstate-based copper hybrids as heterogeneous catalysts for the one-pot synthesis of 2-phenylquinoxalines 2-haloanilines with vinyl azides or 3-phenyl-2-azirines.

One bonded- and one discreted-Lindqvist hexatungstate-based copper hybrids (Cu-POMs) ([Cu2(O)OH(phen)2]2[W6O19]·6H2O (1) and [Cu2(phen)4Cl] [HW6O19]·2H2O (2) (phen = 1,10-phenanthroline)) were controllably synthesized and routinely characterized. Cu-POMs 1-2 consisted of identical [W6O19] unit and similar copper-phen complexes, the two units are bonded via four Cu-O chemical bonds in compound 1; however, compound 2 is discreted and stabilized by intermolecular electrostatic interactions. Importantly, these Cu-POMs catalysts were first applied in the novel reaction for the preparation of 2-phenylquinoxalines via the one-pot coupling and oxidation reactions of 2-haloanilines with vinyl azides or 3-phenyl-2H-azirines under mild conditions, and Cu-POMs 1 showed higher catalytic performance in good yields (79-84%).

Imidazole-directed fabrication of three polyoxovanadate-based copper frameworks as efficient catalysts for constructing C-N bonds.

A synthetic pathway for the directed preparation of three novel polyoxovanadate-based copper frameworks (POVCFs), i.e., [Cu0.

Facile Synthesis of Hierarchical Nanosized Single-Crystal Aluminophosphate Molecular Sieves from Highly Homogeneous and Concentrated Precursors.

The synthesis of hierarchical nanosized zeolite materials without growth modifiers and mesoporogens remains a substantial challenge. Herein, we report a general synthetic approach to produce hierarchical nanosized single-crystal aluminophosphate molecular sieves by preparing highly homogeneous and concentrated precursors and heating at elevated temperatures. Accordingly, aluminophosphate zeotypes of LTA (8-rings), AEL (10-rings), AFI (12-rings), and -CLO (20-rings) topologies, ranging from small to extra-large pores, were synthesized.

Axially chiral 1,4-dihydropyridine derivatives: aggregation-induced emission in exciplexes and application as viscosity probes.

By combining the fluorophores of axially chiral 1,1'-binaphthol (BINOL) and 1,4-dihydropyridine derivatives, axially chiral 1,4-dihydropyridine derivatives (()-/()-2) with aggregation-induced emission (AIE) in exciplexes were designed and synthesized. ()-/()-2 emitted low fluorescence in THF solutions of their locally excited states; however, they emitted red-shifted fluorescence in the aggregate state upon exciplex formation. Moreover, ()-/()-2 showed linear and multi-exponential relationships between their local excited and exciplex fluorescence intensities and the viscosity of the medium, which allowed us to determine the viscosities of different mixed solvents.

Visualization of hydrogen polysulfides in living cells and in vivo via a near-infrared fluorescent probe.

Hydrogen polysulfides (HS, n > 1), as the oxidized forms of HS, have attracted increasing attention these years due to their involvement in signaling transduction and cytoprotective processes. It is necessary to detect HS in living systems for the study of their functions. In this work, we report a BODIPY-based near-infrared emitting fluorescence probe NIR-PHS1, with "turn-on" response, rapid response rate (within 10 min), outstanding selectivity and excellent sensitivity (detection limit = 12 nM) response towards HS.

A BODIPY-based ratiometric probe for sensing and imaging hydrogen polysulfides in living cells.

Hydrogen polysulfides (HS, n > 1) have attracted increasing attention in biological systems due to its redox signaling effect. To illustrate the process of the physiological and pathological roles played by HS, accurate detection is highly desired. In this work, we report a BODIPY-based fluorescent probe (BDP-PHS) for ratiometric HS sensing.

An isophorone-based far-red emitting ratiometric fluorescent probe for selective sensing and imaging of polysulfides.

Recent studies have shown that as members of the reactive sulfur species family and the oxidized forms of HS, hydrogen polysulfides (HS) play important roles in physiological and pathological processes. Therefore, accurate detection of HS levels in living systems is of great significance. In this study, we report an isophorone-based far-red emitting fluorescent probe (RPHS1) for selective ratiometric sensing and imaging of HS.

Solvatochromism, acidochromism and aggregation-induced emission of propeller-shaped spiroborates.

Propeller-shaped pyridyl-enolato-catecholate/-salicyl spiroborates (Sborepy1-6) were synthesized. The complexes Sborepy3-6 show weak emission in fluid solution and aggregation-induced emission enhancement in the aggregation state with large Stokes shifts of 4025-5237 cm-1. Moreover, intense solid-state emissions with high Φf ranging from 25% to 37% were observed for Sborepy3-6 owing to the weak intermolecular interactions in their solid-state.

8-Hydroxy-2-methylquinoline-modified HSiWO: a reusable heterogeneous catalyst for acetal/ketal formation.

A heteropoly acid based organic hybrid heterogeneous catalyst, HMQ-STW, was prepared by combining 8-hydroxy-2-methylquinoline (HMQ) with Keggin-structured HSiWO (STW). The catalyst was characterized elemental analysis, X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), thermogravimetric analysis (TG) and potentiometric titration analysis. The catalytic performance of the catalyst was assessed in the ketalization of ketones with glycol or 1,2-propylene glycol.

Lewis Acid Catalyzed Tandem 1,4-Conjugate Addition/Cyclization of in Situ Generated Alkynyl o-Quinone Methides and Electron-Rich Phenols: Synthesis of Dioxabicyclo[3.3.1]nonane Skeletons.

A versatile Lewis acid catalyzed tandem cyclization of in situ generated alkynyl o-quinone methides ( o-AQMs) with electron-rich phenols has been developed on the basis of the mode involving an intermolecular 1,4-conjugate addition/6-endo cyclization/1,3-aryl shift/intramolecular 1,4-conjugate addition cascade. This reaction provides a new method for expeditious assembly of synthetically and biologically interesting tetracyclic bridged dioxabicyclo[3.3.

New AIE-active pyrimidine-based boronfluoride complexes with high solid-state emission and reversible mechanochromism luminescence behavior.

A new family of pyrimidine-based BF2 complexes () with aggregation-induced emission (AIE) and mechanochromic luminescence properties were developed. These compounds exhibit intense fluorescence in their aggregation/solid-state resulting from their large Stokes shift and AIE. X-ray crystallographic analysis shows that the weak intermolecular interactions by fixing the molecular conformations of are responsible for the intense fluorescence in solid-state.

Benzothiazole-Pyimidine-Based BF2 Complex for Selective Detection of Cysteine.

Due to the similar structure and reactivity of cysteine (Cys), homocysteine (Hcy) and glutathione (GSH), the simultaneous discrimination of Cys over Hcy and GSH by a single fluorescent sensor is still a great challenge. In this work, a benzothiazole-pyimidine-based boron difluoride complex (BPB) was developed as a new fluorescent sensor for Cys. The sensor exhibits a highly selective "turn-on" response to cysteine over Hcy, GSH and other amino acids in aqueous solution at physiological pH.

AIE-active organoboron complexes with highly efficient solid-state luminescence and their application as gas sensitive materials.

Complexation of a boron atom with two of benzothiazole-enolate-based bidentate ligands successfully gave rise to the corresponding BF2-/BPh2-chelated complexes (), which could be considered as novel AIE-active organoboron luminophores. These new luminophores exhibited aggregation-induced emission, and a large Stokes shift in solution. In the solid-state, compounds exhibited intense emission with high quantum yields of 0.

High solid-state luminescence in propeller-shaped AIE-active pyridine-ketoiminate-boron complexes.

Two pyridine-ketoiminate-based organoboron complexes (2 and 3) were developed. 2 and 3 showed very weak emission in low-viscosity organic solvents because of the intramolecular rotation induced non-radiative process. Their emission can be dramatically enhanced by the increase in solvent viscosity or by molecular aggregation in the solid state.

Piezochromic luminescence behaviors of two new benzothiazole-enamido boron difluoride complexes: intra- and inter-molecular effects induced by hydrostatic compression.

Two new propeller-shaped benzothiazole-enamide boron difluoride complexes exhibiting piezochromic luminescence upon mechanical grinding or hydrostatic compression were prepared. The two analogues displayed the red shift in luminescence under high pressure, while compound 2 with ICT effects showed a more sensitive piezochromic response at low pressure (<1.5 GPa).