Nanomechanical Characterization of an Antiferromagnetic Topological Insulator.

The antiferromagnetic topological insulator MnBiTe (MBT) exhibits an ideal platform for investigating unique topological and magnetic properties. While the transport characteristics of magnetic phase transitions in the MBT materials have been extensively studied, the understanding of their mechanical properties and magneto-mechanical coupling remains limited. Here, we utilize nanoelectromechanical systems to probe the intrinsic magnetism in MBT thin flakes through magnetostrictive coupling.

Association between sex hormone binding globulin and metabolic syndrome in US adults: insights from National Health and Nutrition Examination Survey (NHANES) 2013-2016.

Background: Metabolic syndrome (MetS) presents a notable public health challenge on a global scale, exerting a considerable impact on individuals' health and quality of life. There is mounting evidence indicating a robust association between MetS and levels of sex hormones. Therefore, the study aims to explore the relationship between sex hormone binding-globulin (SHBG) and MetS, and to provide evidence that could inform the development of effective prevention strategies for MetS.

Assessment of Corneal Epithelial Changes and Related Factors in Ocular Chronic Graft-Versus-Host Disease (GVHD) by in Vivo Confocal Microscopy.

Purpose: To evaluate corneal epithelial changes and related factors in chronic ocular graft-versus-host disease (oGVHD) patients.

Methods: 21 patients (35 eyes) with chronic oGVHD and 8 patients (12 eyes) without oGVHD after bone marrow transplantation were recruited for assessment involving in vivo confocal microscopy (IVCM) analysis, ocular surface parameter determination and tear cytokine level analysis. The IVCM corneal epithelial scoring system was used to evaluate corneal epithelial changes.

Biomarkers in Ocular Graft-Versus-Host Disease: Implications for the Involvement of B Cells.

Graft-versus-host disease (GVHD) is an immune-mediated inflammatory disease resulting from destruction of host tissue by donor immunoreactive cells and occurs in 30% to 70% of post-hematopoietic stem cell transplantation (HSCT) patients. Ocular involvement occurs in up to 60% to 90% of patients with chronic GVHD. T cells have long been recognized as a key driver of alloreactivity in chronic ocular GVHD (oGVHD).

A murine model of large-scale bone regeneration reveals a selective requirement for Sonic Hedgehog.

Building and maintaining skeletal tissue requires the activity of skeletal stem and progenitor cells (SSPCs). Following injury, local pools of these SSPCs become active and coordinate to build new cartilage and bone tissues. While recent studies have identified specific markers for these SSPCs, how they become activated in different injury contexts is not well-understood.

On the horizon: Hedgehog signaling to heal broken bones.

Uncovering the molecular pathways that drive skeletal repair has been an ongoing challenge. Initial efforts have relied on in vitro assays to identify the key signaling pathways that drive cartilage and bone differentiation. While these assays can provide some clues, assessing specific pathways in animal models is critical.

Scaffolding protein Gab1 regulates myeloid dendritic cell migration in allergic asthma.

Asthma is a common allergic disorder involving a complex interplay among multiple genetic and environmental factors. Recent studies identified genetic variants of human GAB1 as a novel asthma susceptibility factor. However, the functions of Gab1 in lung remain largely unexplored.

Bis(1,3-diethyl-benzimidazolium) tetra-bromidomercurate(II).

In the title compound, (C(11)H(15)N(2))(2)[HgBr(4)], the tetra-coordinated Hg(II) center of the complex anion adopts a distorted tetra-hedral geometry [Hg-Br = 2.5755 (8)-2.623 (11) Å and Br-Hg-Br = 103.