Inhaled turmerone can attenuate nicotine-induced degeneration of the aorta.

Nicotine in secondhand smoke can increase the risk of development of cardiovascular disease in passive smokers through degeneration of the aorta which is one of main pathologies of cardiovascular disease. We speculated that the adverse effect of nicotine can be attenuated by volatile active molecules. As the potential molecule having vasoprotective effect, we focused on turmerone which is major volatile compound in turmeric (Curcuma longa).