Publications by authors named "Shutian Lu"
Article Synopsis
- - Recent advancements in aptamer chemistry enable the development of innovative tools for detecting proteins using a method involving immobilized SOMAmers labeled with a nitroxide radical.
- - When a protein binds to the SOMAmer, it changes the rotational mobility of the attached spin label, which can be measured using electron paramagnetic resonance (EPR) spectroscopy.
- - The study highlights a specific assay combining spin-labeled SOMAmers and fluorescence detection through diamond nitrogen-vacancy centers, offering a versatile method for transforming protein binding events into detectable magnetic signals.
Open-shell organic molecules, including = 1/2 radicals, may provide enhanced properties for several emerging technologies; however, relatively few synthesized to date possess robust thermal stability and processability. We report the synthesis of = 1/2 biphenylene-fused tetrazolinyl radicals and . Both radicals possess near-perfect planar structures based on their X-ray structures and density-functional theory (DFT) computations.
View Article and Find Full Text PDFThe temperature dependence of l-proline interactions with the RNA dodecamer duplex surface exposed after unfolding was quantified using thermal and isothermal titration denaturation monitored by uv-absorbance. The m-value quantifying proline interactions with the RNA duplex surface area exposed after unfolding was measured using RNA duplexes with GC content ranging between 17 and 83%. The m-values from thermal denaturation decreased with increasing GC content signifying increasingly favorable proline interactions with the exposed RNA surface area.
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