Publications by authors named "Shusaku Yanagitani"
Bioorg Med Chem Lett
June 2007
Article Synopsis
- The study describes a process where alkaline protease, Bioprase, catalyzes the transesterification of arbutin with undecylenic acid vinyl ester to create a new arbutin derivative.
- The reaction rate is enhanced by increasing arbutin concentration, achieving over 90% conversion at a concentration of 0.9 M when combined with 2 M undecylenic acid vinyl ester.
- The resulting arbutin ester shows a significant ability to reduce melanin production in B16 melanoma cells, indicating potential applications in skin pigmentation management.
