Photoelectrochemical quenching-recovery biosensor based on NSCQDs/FeO@BiS for the detection of trypsin.

Background: The content of trypsin will change when pancreatic diseases occur, therefore developing a high-performance method for trypsin detection is of great significance for guiding patients on medication plans and improving their prognosis. Photoelectrochemical (PEC) analysis techniques have emerged as a solution to apply for bioassays.

Results: Herein, the FeO@BiS and Nitrogen and sulfur co-doped carbon quantum dots (NSCQDs) were successfully synthesized by a hydrothermal method.

The systematic characterization of multiple components and metabolic profiling of bioactive constituents in Yaobitong capsule by UHPLC/Q-TOF-MS/MS.

Yaobitong capsule is a valuable traditional Chinese medicine prescription (TCMP), which can effectively treat lumbar disc herniation clinically. However, the effective substances in Yaobitong capsule are still unclear due to a lack of metabolic studies. This poses a huge obstacle preventing the clinical safety assessment and quality control of Yaobitong capsule.