Analysis of Clinical Characteristics and Risk Factors for Severe Influenza A and Influenza B in Children.

Purpose: The goal of this study was to develop and validate an online dynamic nomogram system for early differential diagnosis of influenza A and B.

Methods: Patients with severe influenza A and B admitted to Henan Children's Hospital from January 2019 to January 2022 were used as the modeling group (n = 161), and patients admitted from January to September 2023 were used as the validation group (n = 52). Univariate logistic regression and multivariate logistic regression were used to identify the risk variables of severe influenza A and B in children in the modeling group.

Predictive Value of IL-6 and Lymphocyte Subsets for Death in Children With Influenza-Associated Encephalopathy A Retrospective Study.

This study aims to investigate the predictive value of interleukin-6 (IL-6) and lymphocyte subsets for death in children with influenza-associated encephalopathy (IAE). This study included 76 children with IAE who were divided into a death group and a survival group. The differences in the levels of IL-6 and lymphocyte subsets between the two groups were analyzed, and the predictive value of these two parameters was compared by receiver operating characteristic (ROC) curve analysis.

Clinical characteristics of severe influenza as a risk factor for febrile seizures in children: a retrospective analysis.

Objective: To retrospectively analyze the clinical characteristics and independent risk factors of severe influenza combined with febrile seizures, and to provide more basis for early clinical intervention.

Methods: A total of 161 children with severe influenza were collected as study subjects and divided into convulsive (FC) group (40 cases) and non-convulsive (NFC) group (121 cases) according to whether they had febrile seizures. The demographic characteristics and clinical data of the two groups were analyzed.

Clinical analysis of influenza in the neonatal intensive care unit.

Background: The aim was to investigate the clinical characteristics, treatment and prognosis of neonatal influenza.

Methods: The clinical data of 21 neonates who were diagnosed with influenza and admitted to the neonatal intensive care unit of Henan Provincial Children's Hospital, China, between January 2023 and January 2024 were retrospectively analyzed.

Results: A total of 21 patients were admitted, including 14 with influenza A and 7 with influenza B.

Mendelian randomization shows causal effects of birth weight and childhood body mass index on the risk of frailty.

Background: The association between birth weight and childhood body mass index (BMI) and frailty has been extensively studied, but it is currently unclear whether this relationship is causal.

Methods: We utilized a two-sample Mendelian randomization (MR) methodology to investigate the causal effects of birth weight and childhood BMI on the risk of frailty. Instrumental variables ( < 5E-08) strongly associated with own birth weight ( = 298,142 infants), offspring birth weight ( = 210,267 mothers), and childhood BMI ( = 39,620) were identified from large-scale genomic data from genome-wide association studies (GWAS).

Risk factors for pneumonia among children with coinfection of influenza A virus and Mycoplasma pneumoniae.

Objective: To investigate the clinical characteristics and risk factors for pneumonia in children co-infected with influenza A virus (IAV) and Mycoplasma pneumoniae (MP).

Methods: Children who were diagnosed with IAV and MP infection between January and December, 2023 were enrolled and divided into a non-pneumonia group and a pneumonia group. Univariate analysis and logistic regression analysis were used to evaluate each index, and the risk factors for pneumonia caused by coinfection in the two groups were explored.

Necrotizing pneumonia and purulent meningitis caused by bloodstream infection of CA-MRSA in a child: A rare case report.

Case Presentation: We report the case of a girl aged 2 years and 10 months who had fever for 2 days, vomiting, poor mental status for 1 day, and one episode of convulsions.

Symptoms And Signs: The patient experienced a rapid onset of symptoms with fever, vomiting, and convulsions. Upon physical examination on admission, she presented with the following: temperature 38.

Downregulation of CDC20 suppressed cell proliferation, induced apoptosis, triggered cell cycle arrest in osteosarcoma cells, and enhanced chemosensitivity to cisplatin.

Osteosarcoma (OS) is a common malignant bone tumor that occurs in adolescents or children under the age of 20, which is extremely difficult to cure and has a high recurrence rate. Recent studies showed that cell division cycle 20 (CDC20) overexpression is associated with poor prognosis in patients with osteosarcoma. However, the function of CDC20 in osteosarcoma has not been investigated clearly.

[Expression and significance of endothelial microparticles in children with Henoch-Schönlein purpura].

Objective: To study the expression and significance of endothelial microparticles (EMPs) in children with Henoch-Schönlein purpura (HSP).

Methods: A total of 100 previously untreated children with HSP were classified to Henoch-Schönlein purpura nephritis (HSPN) group (n=40) and non-nephritis group (n=60). Thirty healthy children who underwent physical examination were enrolled as control group.

Shape memory materials based on adamantane-containing polyurethanes.

In this contribution, a series of adamantane (AD)-containing polyurethanes were prepared from 1,3-adamantanediol, 1,4-butanediol and hexamethylene diisocyanate, and the influences of AD on the shape memory behavior of polyurethanes were systematically studied. Due to large steric hindrance, AD was able to disrupt the regular arrangement of polyurethane chains and contributed to forming an amorphous domain. It was found that moderate AD-containing polyurethanes had good mechanical properties and broad glass transition, and shape memory tests confirmed these polyurethanes possessed a shape fixation rate of 98% and shape recovery rate of 91% during a dual-shape memory procedure.

Shape Memory Polyurethanes Based on Zwitterionic Hard Segments.

This work aimed at elucidating the influence of zwitterionic hard segments on the structures and properties of shape memory polyurethanes (SMPUs). A series of zwitterionic SMPUs was successfully prepared with -methyldiethanolamine (MDEA), 1,3-propanesultone (1,3-PS), 1,6-hexamethylene diisocyanate (HDI) and polyethylene glycol (PEG6000). The influence of MDEA-PS-based zwitterionic hard segment on structure, morphology, thermal property, shape memory property and cytocompatibility were systematically investigated.

[Significance of serum cholesterol and fibrinogen in evaluating the risk of glomerulosclerosis in children with nephrotic syndrome].

Objective: To investigate the significance of serum cholesterol and fibrinogen (Fib) in evaluating the risk of glomerulosclerosis in children with nephrotic syndrome.

Methods: Sixty-three children with primary nephrotic syndrome were divided into two groups according to their pathological types: minimal change glomerulopathy (MCG) (n=39) and focal segmental glomerulosclerosis (FSGS) groups (n=24). Serum levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), non-HDL-C and Fib and 24-hour urinary protein excretion were retrospectively analyzed.

[A clinico-pathological comparison between Henoch-Schonlein purpura nephritis and IgA nephropathy in children].

Objective: To study the difference in clinico-pathological features between IgA nephropathy (IgAN) and Henoch-Schonlein purpura nephritis (HSPN) in children.

Methods: The medical data of 103 children with HSPN and 61 children with IgAN were retrospectively studied.

Results: There were no significant differences in age, sex and disease course between the HSPN and IgAN groups (P>0.