Three-dimensional ecological drought identification and evaluation method considering eco-physiological status of terrestrial ecosystems.

Ecological drought is a complex process in terrestrial ecosystems where vegetation's eco-physiological functions are impaired due to water stress. However, there is currently a lack of long-term assessment of ecological drought from an eco-physiological perspective. In this study, the standardized ecological drought index (SESNDI) was developed using actual evaporation, root soil moisture, and kernel normalized difference vegetation index via the Euclidean distance method, reflecting ecosystem physiology, water supply capacity, and vegetation status.

Effect of esketamine on haemodynamic fluctuations in patients undergoing hysteroscopic surgery: A prospective, double-blind randomized clinical trial.

Aims: We explored whether esketamine anesthesia during hysteroscopic surgery can reduce intraoperative hemodynamic fluctuations and improve patient benefit.

Methods: A total of 170 patients undergoing hysteroscopic surgery were enrolled, and 151 patients were finally included in the analysis, among which 19 used vasoactive drugs during surgery. Patients were randomly assigned to either the esketamine anesthesia group (E group) or the sufentanil anesthesia group (S group).

Control of climate and physiography on runoff response behavior through use of catchment classification and machine learning.

Understanding of runoff response changes (RRC) is essential for water resource management decisions. However, there is a limited understanding of the effects of climate and landscape properties on RRC behavior. This study explored RRC behavior across controls and predictability in 1003 catchments in the contiguous United States (CONUS) using catchment classification and machine learning.

Curcumin Alleviates β Amyloid-Induced Neurotoxicity in HT22 Cells via Upregulating SOD2.

Curcumin protects neuronal cells exposed to β amyloid (Aβ); the mechanism, however, is still obscure. The aim of this study is to determine whether the type 2 superoxide dismutase (SOD2) mediates curcumin-induced protective effects in Aβ-treated neuronal cells. In this study, the HT22 neuronal cells were exposed to Aβ to imitate neuronal injury in Alzheimer's disease (AD).

Risk factors for HIV/syphilis infection and male circumcision practices and preferences among men who have sex with men in China.

Objective: To investigate factors associated with HIV infection and the frequency and willingness of male circumcision among men who have sex with men (MSM) in Chengdu city, China.

Methods: A cross-sectional survey provided information on participants' demographics, risk behaviors, circumcision, and uptake of HIV prevention services.

Results: Of 570 participants, 13.

Electrochemiluminescence immunosensor for tumor markers based on biological barcode mode with conductive nanospheres.

A novel sandwich-type electrochemiluminescence (ECL) immunosensor was developed for highly sensitive and selective determination of tumor markers based on biological barcode mode. N-(4-aminobutyl)-N-ethylisoluminol (ABEI) and the second antibody (Ab2) were simultaneously immobilized on conductive nanospheres to construct ABEI/Ab2-CNSs probes, which could form sandwich immunocomplex by Ab2 and emit ECL signals by ABEI. The gold layer coated on the surface of the conductive nanospheres could extend the outer Helmholtz plane (OHP) of the ECL immunosensor effectively.

Multiplex electrochemiluminescence immunoassay of two tumor markers using multicolor quantum dots as labels and graphene as conducting bridge.

A multiplex electrochemiluminescence (ECL) immunoassay for simultaneous determination of two different tumor markers, alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA), using multicolor quantum dots as labels and graphene as conducting bridge was developed. Herein, a typical sandwich immune complex was constructed on the glass carbon electrode, with QDs525 and QDs625 labeled on secondary anti-AFP and anti-CEA antibodies, respectively, thus to obtain distinguishable ECL signals. Because most of those QDs labeled on secondary antibodies were beyond the space domain of the ECL reaction, graphene was used as a conducting bridge to promote the electron transfer between QDs and the electrode, leading to about 30-fold enhancement of the ECL intensity.