Publications by authors named "Shupak A"

Background: Only scant information is available regarding the bacteriology of acute otitis media (AOM) in neonates.

Objectives: To investigate the bacteriology of AOM post the introduction of Pneumococcal Conjugate Vaccine (PCV13) in children younger than 3 months and its relation to the mode of delivery.

Methods: Retrospective bacteriological analysis of middle ear fluids taken from children younger than 60 months suffering from AOM.

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The video head impulse test (vHIT) is a new tool in the vestibular tests' arsenal. It is based on the clinical Head Impulse Test, where the integrity of the vestibulo-ocular reflex is tested by high frequency excitation of the semi-circular canals. The vHIT system is composed of an accelerometer measuring the head movements, and a high frequency infra-red camera for eye tracking mounted on a light-weighted goggles.

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Introduction: While the bedside head impulse test evaluates the presence of refixation saccades (RS) as a measure of failing vestibulo-ocular reflex (VOR) the VOR gain calculated by the video head-impulse test (vHIT) is considered the primary measure for semicircular canal function while the role RS is still under evaluation.

Aims: To evaluate the benefit of various RS characteristics towards the diagnosis of the left horizontal semicircular function by vHIT.

Methods: The vHIT recordings of 40 patients with left sided horizontal VOR gains <0.

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Article Synopsis
  • - A woman experienced severe right ear hearing loss and vertigo after skydiving, leading to a diagnosis of a perilymph fistula caused by barotrauma.
  • - The condition was confirmed through various tests, including a video head impulse test, which indicated impaired function in her inner ear and showed promising results post-surgery with improved test scores.
  • - An exploratory tympanotomy revealed a leak in the inner ear, which was fixed; while her hearing showed minor improvements, it remained non-functional, and the use of video head impulse tests was highlighted as a first in evaluating vestibular issues related to this condition.
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Objective: The therapeutic effects of antimotion sickness medications involve suppression of several components along the vestibular system. Scopolamine-based medications have proved to be the most effective anti-seasickness agents. However, there is high variability in individual responses.

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Introduction: Current clinical practice considers the vestibulo-ocular reflex (VOR) gain as registered by the video head impulse test (vHIT) as the primary measure for semicircular canal function, while the role of the re-fixation saccades (RSs) is still under evaluation. The goal of the study was to appraise the added benefit of RS towards the improvement of vHIT diagnostic accuracy in cases of suspected left horizontal semicircular canal dysfunction.

Methods: The vHIT recordings of 40 patients with left-sided horizontal VOR gains <0.

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Objective: Bacteriology and antibiotic resistance trends changed considerably following introduction of the pneumococcal conjugate vaccines (PCV) 7 and 13, with differences between geographic regions. The objective of this study was to evaluate changes in acute otitis media (AOM) bacteriology and antibiotic susceptibility from the pre-vaccination period (2002-2008) to after the introduction of PCV13 (2010-2019) in northern Israel.

Methods: Data were collected from 3277 middle ear fluid (MEF) cultures and 4822 common AOM-generating pathogens of children aged <5 years with otitis media, taken during 2002-2019.

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The functional integrity of the inferior vestibular nerve (IVN) may be evaluated by the cervical vestibular evoked myogenic potential (cVEMP) response, which requires signal transmission via the nerve. As functional integrity of the IVN innervating the posterior semicircular canal is required to produce the typical positioning vertigo and nystagmus characterizing posterior canal benign paroxysmal positional vertigo (PCBPPV), we hypothesized that normal cVEMPs would be found in most PCBPPV patients. Twenty-four PCBPPV patients participated in a prospective cohort study.

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Introduction: Previous studies have reported an association between reduced bone mineral density and the occurrence of benign paroxysmal positional vertigo, balance impairment, and saccular dysfunction. Furthermore, the results of recent animal studies have raised the possibility that vestibular dysfunction could affect bone remodeling and bone mass. The goal of the study was to compare bone mineral density of patients suffering from definite Ménière's disease to that of a matched control group.

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We conducted a study to compare how well the head impulse test (HIT), without and with eye-movement recordings, would predict videonystagmographic (VNG) caloric test lateralization when performed by a resident and an experienced otoneurologist. This prospective, open-label, blinded study was conducted in an ambulatory tertiary care referral center. Our study population was made up of 60 patients-29 men and 31 women, aged 20 to 82 years (mean: 56.

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Objective: To compare the hearing and otoacoustic emissions (OAE) outcome of stapedotomy employing 0.4 and 0.6 mm diameter prostheses.

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VATER association is a nonrandom occurrence of congenital malformations: vertebral defects, anal atresia, tracheoesophageal fistula, renal defects, and radial bone anomalies. We report the case of a 19-year-old man with a childhood diagnosis of VATER association, who presented to the motion sickness clinic with severe seasickness. We discuss the clinical and laboratory diagnosis of vestibular pathophysiology, which was confirmed by MRI of lateral semicircular canal and vestibule dysplasia.

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Intralabyrinthine schwannomas (ILSs) are uncommon benign tumors that originate in the Schwann cell sheath of the intralabyrinthine distal branches of the vestibulocochlear nerve. They have no initial involvement in the internal auditory canal, although that might develop later. These lesions can arise inside the cochlea, originate in the vestibule or, in rare cases, develop in the semicircular canals.

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Susac's syndrome (SS) is a disease of the microvasculature of the retina, brain, and inner ear. We describe a patient with unusual manifestations of SS with possible involvement of the brainstem, cardiac arrhythmia, and MRI findings lacking the characteristic lesions found in Susac's syndrome.

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Mass stranding of cetaceans (whales and dolphins), in close association with the activity of naval sonar systems, has been reported on numerous occasions. Necropsy showed bubble-associated lesions similar to those described in human decompression sickness (DCS). We examined the hypothesis that exposure to underwater sound may potentiate DCS.

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Objective: To evaluate the role of otoacoustic emissions (OAEs) in the prediction of idiopathic sudden sensorineural hearing loss (ISSNHL) outcome.

Study Design: Open-label prospective study.

Setting: Tertiary referral medical center.

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Objective: To examine the role of intratympanic Dexamethasone (ITD) in the prevention of Cisplatin-induced hearing loss.

Study Design: Prospective randomized controlled clinical trial.

Setting: Tertiary referral center.

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Background: Exposure to unfamiliar motion patterns commonly results in motion sickness and a false perception of motion, termed mal de debarquement, on the return to stable conditions.

Objective: To investigate whether motion sickness severity is correlated with the duration and severity of mal de debarquement; to study the possible preventive effect of projecting earth-referenced scenes (an artificial horizon) during exposure to motion on the development of mal de debarquement.

Methods: Thirty subjects were exposed to the recorded motion profile of a boat in a 3-degrees-of-freedom ship motion simulator.

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Objective: Seasickness may impose severe limitations on the performance of ships' crew. Cervical vestibular evoked myogenic potentials (cVEMP) assess the function of the saccule, the organ responsible for monitoring vertical linear acceleration, which has been found to be the most provocative motion stimulus in the evolution of motion sickness. We used the cVEMP test in a prospective evaluation of susceptibility and habituation to seasickness.

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Article Synopsis
  • The study aimed to determine if projecting Earth-referenced visuals during simulated motion could reduce motion sickness and improve performance.
  • Thirty participants prone to motion sickness were tested in a motion simulator, experiencing visual scenes while undergoing various performance assessments over a 120-minute period.
  • Results showed a reduction in motion sickness severity but no improvement in cognitive or motor skills, suggesting that while visual aids may help with discomfort, they do not enhance performance for those actively operating vessels.
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Objectives: To describe the characteristics and outcome of vertigo in a pediatric population.

Patients: All children and adolescents presenting with vertigo to a tertiary otoneurology clinic between the years 2003-2010 were included in the study.

Results: Thirty-seven patients with a mean age of 14 years were evaluated.

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