A causal association between obesity and constipation: a two-sample bidirectional Mendelian randomization study and meta-analysis.

Objective: Observational studies suggest a potential link between obesity and constipation, but existing results are conflicting. Therefore, we conducted a Mendelian randomization (MR) study and meta-analysis to assess the causal relationship between obesity and the risk of constipation.

Methods: In this study, independent genetic variants closely related to constipation were acquired from a genome-wide association study (GWAS) to analyze the relationship between genetically predisposed obesity and the risk of constipation.

Observer-Based Self-Triggered Resilient Control for Multiagent Systems: A k-Connected Graph Construction Approach.

This article investigates the problem of the fully distributed self-triggered secure synchronization control for multiagent systems (MASs) under communication link denial-of-service (CLDoS) attacks. First, an algorithm for constructing a k -connected graph is designed to reduce the impact of CLDoS attacks on MASs. Based on which, a fully distributed observer-based resilient control scheme is co-designed to reduce the dependence on the communication topology information.

The differences between fecal microbiota and intestinal fluid microbiota in colon polyps: An observational study.

Generally, intestinal microbiota can be classified into intestinal cavity microbiota and mucosal microbiota, among which, the former is the default type. This study aimed to identify the differences between fecal microbiota and intestinal fluid microbiota in colon polys.This study enrolled patients with colon polys who met the Rome-III criteria to carry out 16s rDNA gene sequencing.