Autodegradable Polymers: Complete Degradation without Any Trigger, Tunable Performance, and Biomedical Applications.

Degradable polymers are an emerging research interest. The innovation of new degradable polymers for biomedical applications is challenging due to strict demands including nontoxicity of polymers and degraded products, complete degradation to avoid polymer residues in the body, and other suitable properties. Here, we demonstrate a series of degradable polymers for sustained-release drug applications synthesized by the alternating copolymerization of cyclic anhydrides and Schiff bases.