Publications by authors named "Shunya Nishioka"
Article Synopsis
- Triple-negative breast cancer (TNBC) is challenging to treat, with cancer stem cells (CSCs) contributing to its recurrence and spread.
- Researchers developed a new adenoviral vector (Ad-CD44-N-HIF-3α4) that harnesses a synthetic Notch receptor to target CSCs by using CD44 as a decoy, effectively disrupting cancer cell signals.
- In mouse studies with a highly invasive TNBC cell line, the injection of this vector showed promising antitumor effects, suggesting it could be a potential treatment for TNBC patients.
