The promoter aberrant methylation status of TMEM130 is associated with gastric cancer.

Background And Aims: Gastric cancer (GC) is a malignant tumor that seriously affects human health and Epstein-Barr virus (EBV)-associated gastric cancer (EBVaGC) is a molecular subtype of GC. This study aims to determine the relationship between the methylation status of the TMEM130 gene and GC, and to explore the influence of EBV infection.

Methods: qRT-PCR was conducted to investigate the transcriptional expression of TMEM130 in GC.