Publications by authors named "Shuntaro Matsushima"
Article Synopsis
- The study explores the controversial role of primary tumor resection (PTR) in patients with de novo stage IV breast cancer (DnIV BC) and its potential surgical benefits based on clinical outcomes.
- Researchers analyzed data from patients who received systemic therapies and underwent PTR between 2004 and 2022, finding notable differences in progression-free survival (PFS) and overall survival (OS) between those who had surgery and those who did not.
- Results suggest that a longer duration of effective systemic therapy (over 8.1 months) and a low neutrophil-to-lymphocyte ratio (NLR ≤ 3) can indicate the potential advantages of PTR, aiding in timing decisions for surgery in DnIV BC patients
A 56-year-old healthy man who was a current smoker died from fulminant tracheobronchial aspergillosis despite a month of treatment with a combination of intravenous anti-fungal agents that had been started immediately after the diagnosis. This case report is important for understanding and managing fulminant Aspergillus infections in healthy subjects, although the pathogenesis and underlying pathways are still unknown.
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