Publications by authors named "Shunsuke Tano"

Article Synopsis
  • The study assessed the safety and effectiveness of using aggressive hydration and rectal non-steroidal anti-inflammatory drugs to prevent pancreatitis after an ERCP procedure.
  • Conducted at 12 medical centers with 231 patients, the trial found that only 5.6% developed post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) after treatment.
  • Results indicate that this combined approach is a safe and effective preventive strategy, including for elderly patients.
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A 57-year-old man with a history of tuberculosis (TB) was found to have a pancreatic head mass, accompanied by stenosis of the common bile duct. Due to the inherent difficulty in differentiating pancreatic carcinoma from an inflammatory mass, endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB) was thus performed. The pathological findings confirmed granuloma with caseous necrosis, and the results of the QuantiFERON TB2G test were positive.

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Objectives: This study aimed to clarify whether pretreatment human equilibrative nucleoside transporter (hENT1) expressions in endoscopic ultrasonography-guided fine-needle aspiration biopsy (EUS-FNAB) specimens obtained from resectable, borderline resectable, and locally advanced unresectable pancreatic ductal adenocarcinoma (PDAC) are concordant with those in the resected specimen after gemcitabine-based chemoradiotherapy (Gem-CRT) and to validate the utility of hENT1 expression using EUS-FNAB samples as a prognostic marker.

Methods: We evaluated the relationship between hENT1 expressions assessed by immunohistochemical staining and clinical outcomes in 51 of 76 patients with PDAC who were diagnosed by EUS-FNAB and received preoperative Gem-CRT.

Results: The concordance rate of hENT1 expressions was 89.

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A 66-year-old Japanese man consulted our institution due to paroxysmal and repetitive bouts of fever and abdominal pain that had persisted for more than one week. Capsule and double-balloon endoscopy (DBE) showed petal-shaped mucosal redness with white hemming in the jejunum and ileum, and histopathology of the biopsy specimens revealed villous atrophy and cryptitis with extensive severe neutrophil infiltration. A genetic examination disclosed compound heterozygous MEFV mutations (E84K, P369S), and familial Mediterranean fever was diagnosed.

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A retrospective cohort study was conducted in 55 symptomatic patients with amebic colitis that visited at St. Luke's International Hospital and Mie University Hospital from 1994 through 2013. To diagnose amebic colitis, 40 patients underwent total colonoscopy within 1 week after hospital visiting and before receiving any treatment.

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Article Synopsis
  • The study investigates the effectiveness of performing second-look (D1) and third-look (D7) esophagogastroduodenoscopy (EGD) with endoscopic hemostatic therapy (EHT) to prevent bleeding after endoscopic submucosal dissection (ESD) in patients with early gastric cancer or adenoma.
  • Findings show a low post-ESD clinical bleeding rate of 2.6%, with significant risk factors identified as being under age 65 and using antithrombotic drugs.
  • The results suggest that the sequential strategy of using D1 and D7 look EGDs is promising for reducing post-ESD bleeding, particularly influenced by tumor characteristics and previous EHT interventions.
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Objective: We aimed to confirm the effect of combined treatment with celecoxib and rebamipide would be more effective than celecoxib alone for prevention of upper gastrointestinal (GI) events.

Methods: Patients with rheumatoid arthritis, osteoarthritis, and low back pain were enrolled in this study. Patients were randomized to two groups: a monotherapy group (100 mg celecoxib twice daily) and a combination therapy group (add on 100 mg of rebamipide three times a day).

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Background And Aim: Various techniques of endoscopy have been developed to treat rectal carcinoids. This retrospective study aimed to evaluate the feasibility and efficacy of endoscopic submucosal dissection for the treatment of rectal carcinoids smaller than 10 mm in diameter.

Patients And Methods: A total of 18 consecutive patients were enrolled with 20 carcinoid tumors that had the following characteristics: the diagnosis of a rectal carcinoid smaller than 10 mm, no endoscopic evidence of muscularis propria invasion, and no evidence of lymph node or distant metastasis (11 men and seven women; median age, 69 years; median tumor size, 4 mm).

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  • The study investigated the effectiveness of various magnifying endoscopy techniques in identifying and outlining residual or recurrent gastric neoplasms following endoscopic treatment.
  • 15 patients underwent multiple magnifying endoscopic procedures, revealing more lesions than traditional methods and ensuring all were successfully resected.
  • Results indicated that magnifying endoscopy can accurately detect and delineate gastric neoplasms, aiding in better treatment outcomes.
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Article Synopsis
  • Endoscopic mucosal resection (EMR) is a common but challenging procedure for treating early gastric cancer (EGC), especially concerning the identification of cancer-free resection margins, particularly with piecemeal techniques.
  • A study involving 149 EGC patients examined the risks, local recurrence rates, and mortality associated with piecemeal EMR compared to en bloc EMR, tracking outcomes over 10 years with annual follow-ups.
  • Results indicated that although there were significant differences in unclear margins between the two methods, EMR was conducted without complications, and a larger lesion size (over 20 mm) increased the risk for necessitating piecemeal EMR.
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