Synopsis of recent research by authors named "Shunsuke Okamura"
- Shunsuke Okamura's research primarily focuses on the mechanisms of drug resistance in bladder cancer, specifically examining the roles of microRNAs and various inhibitors to develop novel therapies for chemotherapy-resistant cases.
- His recent studies have identified specific microRNAs, such as miR-424-5p and microRNA-99a-5p, that are involved in the regulation of drug resistance and cellular senescence in bladder cancer cells treated with cisplatin and gemcitabine.
- Additionally, Okamura's work explores the potential of targeting metabolic pathways, such as glutamine metabolism through SLC1A5, and utilizing new therapeutic agents like Rapalink-1 to combat resistance in renal cell carcinoma and provide alternative treatment options.