Integrated Evaluation of Inflammatory, Nutritional, and Sarcopenia Markers to Predict Survival in Metastatic Breast Cancer Patients.

Background/aim: The prognosis of a cancer patient is influenced by the tumor-related factors, as well as by various patient-related factors. We evaluated the association between inflammatory and nutritional factors and their outcomes, including the prognosis and therapeutic course, in patients with metastatic breast cancer.

Patients And Methods: In this observational retrospective study, we evaluated 35 patients.

Transplantation of chemically-induced liver progenitor cells ameliorates hepatic fibrosis in mice with diet-induced nonalcoholic steatohepatitis.

Unlabelled: Chemically-induced liver progenitors (CLiPs) have promising applications in liver regenerative medicine. We aimed to clarify the efficacy of CLiPs for ameliorating fibrosis in a diet-induced nonalcoholic steatohepatitis rat model, since nonalcoholic fatty liver disease is currently recognized as the most common form of chronic liver disease in developed countries.

Methods: Primary mature hepatocytes were isolated from 7-week-old male Wistar rats.

Application of laparoscopic distal pancreatectomy for normal anatomy after hiatal hernia repair: A case report.

We describe a case of pancreatic tumor associated with a giant type IV hiatal hernia that had prolapsed into the posterior mediastinum. Hiatal hernia repair should be performed first because it enables laparoscopic distal pancreatectomy to be performed in the normal anatomical position.

A case of retroperitoneal abscess caused by infection of urachal remnant.

Infection of urachal remnant may cause recurrent abscesses. In the current case report, we describe a urachal remnant infection leading to a retroperitoneal abscess, which is an extremely rare condition. In such cases, the recommended treatment is urachal remnant resection.

A comparison of postoperative pain between transumbilical and suprapubic incision in laparoscopic liver resection.

Background: In laparoscopic liver resection, few reports have investigated the influence of type of incision on postoperative pain in laparoscopic liver resection. We therefore conducted the present study to clarify the difference in postoperative pain between two types of incision.

Methods: Nineteen patients who underwent laparoscopic lateral sectionectomy were enrolled.

Successful induction of human chemically induced liver progenitors with small molecules from damaged liver.

Background: Human chemically induced liver progenitors (hCLiP) induced by small molecules produced by mature hepatocytes can potentially overcome issues related to hepatocyte transplantation, such as graft rejection or donor shortage. However, to our knowledge, no studies have explored the induction of hCLiP from mature hepatocytes (MHs) in damaged liver, indicated for liver transplantation.

Methods: Liver tissues were collected from surgically resected livers, including damaged livers, of 86 patients at our department, and hepatocytes were isolated using the collagenase perfusion method.

Carcinosarcoma of the Thoracic Esophagus That Presented as Focal Ulcerative Lesion.

Esophageal carcinosarcoma is a rare malignant tumor composed of both carcinomatous and sarcomatous elements. We report a case of esophageal carcinosarcoma in a 56-year-old woman with dysphagia. Esophageal ulcerative tumors were detected by endoscopy and resected by thoracoscopic esophagectomy.

Living donor liver transplantation for congenital absence of portal vein in portal venous reconstruction with a great saphenous vein graft.

Background: Congenital absence of portal vein (CAPV) is a rare structural anomaly in which the portal vein (PV) blood that normally flow into the liver directly drains into the systemic venous system through other collateral circulation. Congenital portal vein shunts (CPSs) is classified into types I and II according to the absence or presence of the intrahepatic portal vein, respectively. The CPS type I is also known as CAPV.

Severe neutrophilic leukocytosis as a progression marker in granulocyte colony-stimulating factor-producing squamous cell carcinoma of the esophagus.

There are very few reports of esophageal carcinoma producing granulocyte colony-stimulating factor (G-CSF). G-CSF-producing esophageal squamous cell carcinoma is an extremely aggressive carcinoma. Leukocyte counts, neutrophil counts, and serum C-reactive protein levels may be markers of its progression.

[Fibrin-related Markers in Acute Phase of Pulmonary Embolism and Deep Venous Thrombosis].

Background: The fibrin-related markers are considered to be useful in diagnosing pulmonary embolism (PE) and deep vein thrombus (DVT). We measured D-dimer (DD) and soluble fibrin monomer complex (SFMC) in these cases, in order to examine the usefulness of these markers.

Methods: PE patients (P group: 14 cases) and DVT patients (D group : 16 cases) treated in our hospital, were examined.

[Subtypes of acute ischemic stroke and neurological prognosis].

Background: TOAST diagnosis is used in acute ischemic stroke. There is no evidence about the relationship between stroke subtypes classified by TOAST diagnosis and prognosis. We investigated prognosis of cardioembolic stroke (CE) and atherothrombotic stroke (AT) after intravenous recombinant tissue plasminogen activator (rt-PA), to clarify relationship between stroke subtypes and prognosis.